Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50039421
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346951(CHEMBL1795714 | CHEMBL1795711)
Affinity DataKd:  0.0270nMAssay Description:Binding affinity to KOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795715 | CHEMBL1795712)
Affinity DataKd:  0.0500nMAssay Description:Binding affinity to KOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]-IBOxyA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795716 | CHEMBL1795713)
Affinity DataKd:  0.0800nMAssay Description:Binding affinity to MOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795715 | CHEMBL1795712)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H]-U69593 from KOR-1 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346951(CHEMBL1795714 | CHEMBL1795711)
Affinity DataKd:  0.110nMAssay Description:Binding affinity to MOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)
Affinity DataKi:  0.150nMAssay Description:Displacement of [125I]-IBNtxA from KOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)
Affinity DataKi:  0.190nMAssay Description:Displacement of [125I]-IBNalA from KOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataKi:  0.190nMAssay Description:Displacement of [125I]-IBNalA from KOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795715 | CHEMBL1795712)
Affinity DataKd:  0.220nMAssay Description:Binding affinity to MOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataKi:  0.230nMAssay Description:Displacement of [125I]-IBNtxA from KOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346951(CHEMBL1795714 | CHEMBL1795711)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]-U69593 from KOR-1 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346951(CHEMBL1795714 | CHEMBL1795711)
Affinity DataKd:  0.240nMAssay Description:Binding affinity to DOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [125I]-IBNalA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [125I]-IBNtxA from DOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50326673((levallorphan)17-allyl-(1R,9R)-17-azatetracyclo[7....)
Affinity DataKi:  0.480nMAssay Description:Displacement of [125I]-IBOxyA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM21864(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]-IBNalA from DOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [125I]-IBOxyA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346951(CHEMBL1795714 | CHEMBL1795711)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]-DPDPE from DOR-1 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795715 | CHEMBL1795712)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]-DAMGO from MOR-1 expressed in CHO cells after 150 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.730nMAssay Description:Displacement of [125I]-IBNtxA from KOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.950nMAssay Description:Displacement of [125I]-IBNalA from KOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346948(CHEMBL1795717 | CTAP-NH2)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-IBOxyA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]-IBNtxA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50326673((levallorphan)17-allyl-(1R,9R)-17-azatetracyclo[7....)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]-IBNtxA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]-IBNtxA from DOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]-IBOxyA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50326673((levallorphan)17-allyl-(1R,9R)-17-azatetracyclo[7....)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I]-IBNalA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]-IBNalA from DOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795716 | CHEMBL1795713)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-DAMGO from MOR-1 expressed in CHO cells after 150 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [125I]-IBOxyA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346948(CHEMBL1795717 | CTAP-NH2)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]-IBNtxA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]-IBNalA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]-IBNalA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346951(CHEMBL1795714 | CHEMBL1795711)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-DAMGO from MOR-1 expressed in CHO cells after 150 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795715 | CHEMBL1795712)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to DOR-1 expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346952(CHEMBL1795715 | CHEMBL1795712)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]-DPDPE from DOR-1 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [125I]-IBNalA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346948(CHEMBL1795717 | CTAP-NH2)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]-IBNalA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]-IBNtxA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [125I]-IBNtxA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]-IBNtxA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795716 | CHEMBL1795713)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-U69593 from KOR-1 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346953(CHEMBL1795716 | CHEMBL1795713)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-DPDPE from DOR-1 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed