Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50043095
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM18692(CHEMBL124881 | (2S)-N-[4-cyano-3-(trifluoromethyl)...)
Affinity DataEC50:  31nMAssay Description:Displacement of [3H]R1881 from AR in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataEC50:  49nMAssay Description:Displacement of [3H]R1881 from AR in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50435992(CHEMBL2392006)
Affinity DataIC50: 125nMAssay Description:Inhibition of human truncated CYP17A1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50435997(CHEMBL2392007)
Affinity DataIC50: 206nMAssay Description:Inhibition of human truncated CYP17A1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50435990(VN/124 | VN/124-1 | TOK-001 | GALETERONE | US96112...)
Affinity DataEC50:  670nMAssay Description:Displacement of [3H]R1881 from AR in human LNCaP cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50435990(VN/124 | VN/124-1 | TOK-001 | GALETERONE | US96112...)
Affinity DataIC50: 752nMAssay Description:Inhibition of human truncated CYP17A1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataEC50:  915nMAssay Description:Displacement of [3H]R1881 from AR in human LNCaP cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM18692(CHEMBL124881 | (2S)-N-[4-cyano-3-(trifluoromethyl)...)
Affinity DataEC50:  1.40E+3nMAssay Description:Displacement of [3H]R1881 from AR in human LNCaP cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50435993(CHEMBL2392004)
Affinity DataIC50: 9.37E+4nMAssay Description:Inhibition of human truncated CYP17A1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50435994(CHEMBL2392003)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of human truncated CYP17A1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50435996(CHEMBL2392008)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human truncated CYP17A1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50435995(CHEMBL2391999)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of human truncated CYP17A1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50435991(CHEMBL2391997)
Affinity DataIC50: 2.58E+5nMAssay Description:Inhibition of human truncated CYP17A1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed