Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50005621
TargetTubulin beta-3 chain(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of p-gp overexpressed in human SKOV3/M6-6 isogenic cells after 48 hrs by sulforhodamine B assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetTubulin beta-3 chain(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50001839(CHEMBL428647 | taxol | PACLITAXEL)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetTubulin beta-3 chain(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50493263(CHEMBL2425924)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50493263(CHEMBL2425924)
Affinity DataIC50: 16nMAssay Description:Inhibition of p-gp overexpressed in human SKOV3/M6-6 isogenic cells after 48 hrs by sulforhodamine B assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetTubulin beta-3 chain(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50493264(CHEMBL1824506)
Affinity DataIC50: 24nMAssay Description:Inhibition of beta3 tubulin overexpressed in human HeLa cells after 48 hrs by SRB assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50493264(CHEMBL1824506)
Affinity DataIC50: 44nMAssay Description:Inhibition of p-gp overexpressed in human SKOV3/M6-6 isogenic cells after 48 hrs by sulforhodamine B assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of pig brain tubulin assembly preincubated for 15 mins followed by GTP addition measured after 20 mins by spectrophotometric analysis in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50493263(CHEMBL2425924)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of pig brain tubulin assembly preincubated for 15 mins followed by GTP addition measured after 20 mins by spectrophotometric analysis in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50493264(CHEMBL1824506)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of pig brain tubulin assembly preincubated for 15 mins followed by GTP addition measured after 20 mins by spectrophotometric analysis in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50001839(CHEMBL428647 | taxol | PACLITAXEL)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of p-gp overexpressed in human SKOV3/M6-6 isogenic cells after 48 hrs by sulforhodamine B assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed