Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50035781
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017729BDBM50017729(CHEMBL545239 | 4-Ethylamino-7,7-dioxo-4,5,6,7-tetr...)
Affinity DataKi:  0.690nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041029BDBM50041029(CHEMBL417975 | 4-Isopropylamino-7,7-dioxo-4,5,6,7-...)
Affinity DataKi:  0.700nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041029BDBM50041029(CHEMBL417975 | 4-Isopropylamino-7,7-dioxo-4,5,6,7-...)
Affinity DataKi:  0.700nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367851BDBM50367851(CHEMBL1788291)
Affinity DataKi:  0.820nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017728BDBM50017728(CHEMBL543604 | 7,7-Dioxo-4-propylamino-4,5,6,7-tet...)
Affinity DataKi:  1.10nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017726BDBM50017726(CHEMBL554854 | 4-Butylamino-7,7-dioxo-4,5,6,7-tetr...)
Affinity DataKi:  1.80nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017732BDBM50017732(CHEMBL545245 | 4-Methylamino-7,7-dioxo-4,5,6,7-tet...)
Affinity DataKi:  2.30nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017731BDBM50017731(CHEMBL554091 | 4-Amino-7,7-dioxo-4,5,6,7-tetrahydr...)
Affinity DataKi:  3.70nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452418BDBM50452418(CHEMBL2092886)
Affinity DataKi:  6.20nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017727BDBM50017727((S)-4-Hydroxy-7,7-dioxo-4,5,6,7-tetrahydro-7lambda...)
Affinity DataKi:  6.80nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017730BDBM50017730(CHEMBL555182 | 4-Diethylamino-7,7-dioxo-4,5,6,7-te...)
Affinity DataKi:  9.30nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367483BDBM50367483(CHEMBL1788205)
Affinity DataKi:  16nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452588BDBM50452588(CHEMBL2092885)
Affinity DataKi:  16nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  22nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Merck Sharp and Dohme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041028BDBM50041028((R)-4-Isobutylamino-7,7-dioxo-4,5,6,7-tetrahydro-7...)
Affinity DataKi:  71nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed