Affinity DataIC50: 100nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha [1489-1708](Mus musculus)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of mouse NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha [1489-1708](Mus musculus)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of mouse NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha [1489-1708](Mus musculus)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of mouse NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair