Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50048043
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202376(CHEMBL3919012)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of GST-tagged c-Met (unknown origin) assessed as phosphotyrosine levels preincubated foe 15 mins followed by addition of poly(glutamic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202438(CHEMBL3950207)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of GST-tagged c-Met (unknown origin) assessed as phosphotyrosine levels preincubated foe 15 mins followed by addition of poly(glutamic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202439(CHEMBL3889870)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of GST-tagged c-Met (unknown origin) assessed as phosphotyrosine levels preincubated foe 15 mins followed by addition of poly(glutamic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202329(GW305178X)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human CDK2/cyclinA expressed in Baculovirus infected T.ni cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202434(GW276655X)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human CDK2/cyclinA expressed in Baculovirus infected T.ni cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202433(CHEMBL411426)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human CDK2/cyclinA expressed in Baculovirus infected T.ni cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202432(CHEMBL410883)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202321(CHEMBL271160)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human CDK2/cyclinA expressed in Baculovirus infected T.ni cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202432(CHEMBL410883)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human CDK2/cyclinA expressed in Baculovirus infected T.ni cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202378(CHEMBL407709)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of human CDK2/cyclinA expressed in Baculovirus infected T.ni cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202436(CHEMBL3982132)
Affinity DataIC50:  9nMAssay Description:Inhibition of GST-tagged c-Met (unknown origin) assessed as phosphotyrosine levels preincubated foe 15 mins followed by addition of poly(glutamic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202435(CHEMBL3969990)
Affinity DataIC50:  9nMAssay Description:Inhibition of GST-tagged c-Met (unknown origin) assessed as phosphotyrosine levels preincubated foe 15 mins followed by addition of poly(glutamic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202434(GW276655X)
Affinity DataIC50:  10nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202329(GW305178X)
Affinity DataIC50:  12nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202289(CHEMBL272389)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CDK2/cyclinA expressed in Baculovirus infected T.ni cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202433(CHEMBL411426)
Affinity DataIC50:  37nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202321(CHEMBL271160)
Affinity DataIC50:  41nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202312(CHEMBL272387)
Affinity DataIC50:  43nMAssay Description:Inhibition of human CDK2/cyclinA expressed in Baculovirus infected T.ni cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202378(CHEMBL407709)
Affinity DataIC50:  43nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202299(CHEMBL411491)
Affinity DataIC50:  60nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 1(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202312(CHEMBL272387)
Affinity DataIC50:  170nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202289(CHEMBL272389)
Affinity DataIC50:  350nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202437(CHEMBL502013)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of GST-tagged Shp2 PTP domain (unknown origin) using DiFMUP as substrate measured after 5 to 10 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM152151(US8987474, HL1-056 (NSC-117199) )
Affinity DataIC50:  4.99E+3nMAssay Description:Inhibition of human GST-tagged Shp2 (205 to 593 residues) expressed Escherichia coli DH5alpha assessed as inhibition of PTP activity using DiFMUP as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50351710(CHEMBL1822572)
Affinity DataIC50:  7.63E+3nMAssay Description:Inhibition of GST-tagged c-Met (unknown origin) assessed as phosphotyrosine levels preincubated foe 15 mins followed by addition of poly(glutamic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202377(CHEMBL3978908)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin) assessed as inhibition of phosphorylation using Ser/Thr 9 peptide as substrate by FRET-based Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202306(CHEMBL3912187)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GST-tagged c-Met (unknown origin) assessed as phosphotyrosine levels preincubated foe 15 mins followed by addition of poly(glutamic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50202375(CHEMBL3918939)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GST-tagged c-Met (unknown origin) assessed as phosphotyrosine levels preincubated foe 15 mins followed by addition of poly(glutamic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed