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Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 50018982
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of human P2Y1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataIC50: 0.120nMAssay Description:Antagonist activity at human P2Y1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118225(ARL 69931MX | Adenosine triphosphate derivative | ...)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at P2Y12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50045598(US9540323, 220 | CHEMBL3314311 | US9540323, exampl...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at human P2Y1 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50167271(CHEMBL3798413)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-2-MeS-ADP from human P2Y12 assessed as inhibition constant incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429537(CHEMBL2333770)
Affinity DataKi:  6nMAssay Description:Inhibition of human P2Y1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429541(CHEMBL2333766)
Affinity DataKi:  7nMAssay Description:Inhibition of human P2Y1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50167273(CHEMBL3797316)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at human P2Y12More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429548(CHEMBL2333759)
Affinity DataKi:  18nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429538(CHEMBL2333767)
Affinity DataKi:  20nMAssay Description:Inhibition of human P2Y1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50268964(Sodium 1-Amino-4-[4-phenylamino-3-carboxyphenylami...)
Affinity DataKi:  21nMAssay Description:Antagonist activity at human P2Y12 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429546(CHEMBL2333761)
Affinity DataKi:  28nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 14(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human P2Y14 expressed in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50373303(CHEMBL256141)
Affinity DataKi:  30nMAssay Description:Inhibition of human P2Y1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429547(CHEMBL2333760)
Affinity DataKi:  33nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 14(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human P2Y14 expressed in rat CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 6(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50454137(CHEMBL1321988)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human P2Y6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429567(CHEMBL2333776)
Affinity DataKi:  47nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429561(CHEMBL2333353)
Affinity DataKi:  48nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429562(CHEMBL2333352)
Affinity DataKi:  69nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50373324(CHEMBL258406)
Affinity DataKi:  70nMAssay Description:Inhibition of human P2Y1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 14(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  74nMAssay Description:Agonist activity at human P2Y14 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429569(CHEMBL2333774)
Affinity DataKi:  75nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429545(CHEMBL2333762)
Affinity DataKi:  77nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 14(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50614414(CHEMBL5271821)
Affinity DataKi:  80nMAssay Description:Antagonist activity at human P2Y14 expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50373323(CHEMBL255306)
Affinity DataKi:  90nMAssay Description:Inhibition of human P2Y1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 6(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50614412(CHEMBL5272895)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human P2Y6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50397203(CHEMBL2172275)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human P2Y12More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 2(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118213(uridine 5'-(tetrahydrogen triphosphate) | UTP | 5'...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human P2Y2 transfected in human 1321N1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 14(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50343128(2-(benzo[d][1,3]dioxol-5-yl)-N-(3-ethylphenyl)-4-o...)
Affinity DataKi:  160nMAssay Description:Antagonist activity at human recombinant P2Y14 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50101892(2-(7-Ethoxy-4-hydroxy-2,2-dioxo-2H-2lambda*6*,9-di...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human P2Y12More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429568(CHEMBL2333775)
Affinity DataKi:  171nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429544(CHEMBL2333763)
Affinity DataKi:  172nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429540(CHEMBL2333768)
Affinity DataKi:  175nMAssay Description:Inhibition of human P2Y1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human pA2 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 2(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50341904([P(1)-(uridine 5')-P(4)-(2'-deoxycytidine 5')tetra...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human P2Y2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 2(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50366480(ATP | ADENOSINE TRIPHOSPHATE)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human P2Y2 transfected in human 1321N1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50045598(US9540323, 220 | CHEMBL3314311 | US9540323, exampl...)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human pA2 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 6(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  300nMAssay Description:Antagonist activity at P2Y6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429559(CHEMBL2333355)
Affinity DataKi:  313nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118229(MRS 2179 | CHEMBL129841)
Affinity DataIC50: 330nMAssay Description:Inhibition of human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 14(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118239(uridine 5'-(trihydrogen diphosphate) | UDP | Uridi...)
Affinity DataEC50:  350nMAssay Description:Antagonist activity at rat P2Y14More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 4(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50118213(uridine 5'-(tetrahydrogen triphosphate) | UTP | 5'...)
Affinity DataEC50:  550nMAssay Description:Agonist activity at human P2Y4 transfected in human 1321N1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429565(CHEMBL2333349)
Affinity DataKi:  607nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50085327(MRS 2286 | Phosphoric acid mono-[4-(2-chloro-6-met...)
Affinity DataIC50: 840nMAssay Description:Agonist activity at human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 4(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50366480(ATP | ADENOSINE TRIPHOSPHATE)
Affinity DataEC50:  1.17E+3nMAssay Description:Antagonist activity at rat P2Y4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 13(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50029031(CHEMBL223344 | 1-Amino-4-{4-[4-chloro-6-(3-sulfo-p...)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at P2Y13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429549(CHEMBL2333758)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [beta-33p]-2-MeS-ADP from human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50429537(CHEMBL2333770)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human P2Y1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 13(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50000029(suramin | SURAMIN HEXASODIUM | CHEMBL265502 | 4-Me...)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at P2Y13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
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