Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50012561
TargetSphingosine-1-phosphate lyase 1(Rat)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558374(CHEMBL4742786)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of rat liver microsomal S1PLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Rat)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50187501(CHEMBL3827445)
Affinity DataKi:  5.00E+3nMAssay Description:Competitive inhibition of rat liver microsomal S1PL using varying levels of [3-3H]-D(+) erythro-sphinganine-1-phosphate as substrate incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558370(CHEMBL4784427)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant human S1PL using RBM13 as fluorogenic substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558370(CHEMBL4784427)
Affinity DataKi:  5.60E+3nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558364(CHEMBL4754006)
Affinity DataKi:  6.30E+3nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558371(CHEMBL4763050)
Affinity DataKi:  9.10E+3nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558371(CHEMBL4763050)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant human S1PL using RBM13 as fluorogenic substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558364(CHEMBL4754006)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant human S1PL using RBM13 as fluorogenic substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558367(CHEMBL4754871)
Affinity DataKi:  1.64E+4nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558368(CHEMBL4748268)
Affinity DataKi:  1.75E+4nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558365(CHEMBL4756827)
Affinity DataKi:  1.90E+4nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558369(CHEMBL4791053)
Affinity DataKi:  2.04E+4nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558367(CHEMBL4754871)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of recombinant human S1PL using RBM13 as fluorogenic substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558368(CHEMBL4748268)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of recombinant human S1PL using RBM13 as fluorogenic substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558365(CHEMBL4756827)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of recombinant human S1PL using RBM13 as fluorogenic substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558366(CHEMBL4763487)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of recombinant human S1PL using RBM13 as fluorogenic substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558369(CHEMBL4791053)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of recombinant human S1PL using RBM13 as fluorogenic substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558366(CHEMBL4763487)
Affinity DataKi:  3.67E+4nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Mouse)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50158336(FINGOLIMOD HYDROCHLORIDE | 2-amino-2-(4-octylphene...)
Affinity DataIC50: 5.24E+4nMAssay Description:Inhibition of mouse liver microsomal S1PL using S1P as substrate incubated for 20 mins by ESI-LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558373(CHEMBL4751297)
Affinity DataIC50: 8.11E+4nMAssay Description:Inhibition of recombinant human S1PL using RBM13 as fluorogenic substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558372(CHEMBL4762682)
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of recombinant human S1PL using RBM13 as fluorogenic substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed