Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with all data for entry = 50010090
TargetTumor necrosis factor receptor superfamily member 16(Mus musculus)
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50535058(CHEMBL4439582)
Affinity DataEC50:  20nMAssay Description:Activation of p75NTR in mouse hippocampal neurons assessed as increase in cell survival after 48 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to D2 receptor in rat brain striatal homogenates after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 16(Mus musculus)
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50535059(CHEMBL4446977)
Affinity DataEC50: <10nMAssay Description:Activation of p75NTR in C57BL/6 mouse brain assessed as suppression of carbachol-mediated persistant firing of entorhinal cortex after 15 mins by cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed