Compile Data Set for Download or QSAR
maximum 50k data
Found 86 Enz. Inhib. hit(s) with all data for entry = 50048990
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataKi:  0.970nMAssay Description:Antagonist activity at human EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataKi:  6.10nMAssay Description:Antagonist activity at rat recombinant EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50107283(AAT-007 | CJ-023 | Grapiprant | MR-10A7 | RQ-00000...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Askat

Curated by ChEMBL
LigandPNGBDBM50107283(AAT-007 | CJ-023 | Grapiprant | MR-10A7 | RQ-00000...)
Affinity DataKi:  20nMAssay Description:Antagonist activity at rat recombinant EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Canis lupus familiaris)
Askat

Curated by ChEMBL
LigandPNGBDBM50107283(AAT-007 | CJ-023 | Grapiprant | MR-10A7 | RQ-00000...)
Affinity DataKi:  24nMAssay Description:Antagonist activity at dog recombinant EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Canis lupus familiaris)
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataKi:  38nMAssay Description:Antagonist activity at dog recombinant EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232546(CHEMBL4103046)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataKi:  1.84E+3nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50107283(AAT-007 | CJ-023 | Grapiprant | MR-10A7 | RQ-00000...)
Affinity DataKi: >5.00E+3nMAssay Description:Antagonist activity at human platelet TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50107283(AAT-007 | CJ-023 | Grapiprant | MR-10A7 | RQ-00000...)
Affinity DataKi: >5.00E+3nMAssay Description:Antagonist activity at human EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50107283(AAT-007 | CJ-023 | Grapiprant | MR-10A7 | RQ-00000...)
Affinity DataKi: >5.00E+3nMAssay Description:Antagonist activity at human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50107283(AAT-007 | CJ-023 | Grapiprant | MR-10A7 | RQ-00000...)
Affinity DataKi: >5.00E+3nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50107283(AAT-007 | CJ-023 | Grapiprant | MR-10A7 | RQ-00000...)
Affinity DataKi: >5.00E+3nMAssay Description:Antagonist activity at human IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50107283(AAT-007 | CJ-023 | Grapiprant | MR-10A7 | RQ-00000...)
Affinity DataKi: >5.00E+3nMAssay Description:Antagonist activity at human FP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataKi: >6.00E+3nMAssay Description:Antagonist activity at human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataKi: >6.00E+3nMAssay Description:Antagonist activity at human platelet TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataKi: >6.00E+3nMAssay Description:Antagonist activity at human IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataKi: >6.00E+3nMAssay Description:Antagonist activity at human FP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232550(CHEMBL4062620)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50355882(CHEMBL591666)
Affinity DataIC50:  6.60nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232545(CHEMBL4078648)
Affinity DataIC50:  8.80nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50:  9.70nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232548(CHEMBL4094572)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232544(CHEMBL4099851)
Affinity DataIC50:  16nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232550(CHEMBL4062620)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232562(CHEMBL4066230)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232563(CHEMBL4095293)
Affinity DataIC50:  29nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232545(CHEMBL4078648)
Affinity DataIC50:  31nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232548(CHEMBL4094572)
Affinity DataIC50:  36nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50355882(CHEMBL591666)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232547(CHEMBL4065183)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232556(CHEMBL4095176)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232560(CHEMBL4061149)
Affinity DataIC50: <50nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232557(CHEMBL4074660)
Affinity DataIC50: <50nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232559(CHEMBL4089315)
Affinity DataIC50: <50nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232558(CHEMBL4095118)
Affinity DataIC50: <50nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232552(CHEMBL4074035)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232572(CHEMBL4064393)
Affinity DataIC50:  61nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232573(CHEMBL4102314)
Affinity DataIC50:  94nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232551(CHEMBL4084355)
Affinity DataIC50:  94nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232562(CHEMBL4066230)
Affinity DataIC50:  101nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232546(CHEMBL4103046)
Affinity DataIC50:  104nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232549(CHEMBL4092846)
Affinity DataIC50:  124nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232575(CHEMBL4102924)
Affinity DataIC50:  137nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232563(CHEMBL4095293)
Affinity DataIC50:  143nMAssay Description:Antagonist activity at human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232555(CHEMBL4086496)
Affinity DataIC50:  175nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232576(CHEMBL4072974)
Affinity DataIC50:  181nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 86 total ) | Next | Last >>
Jump to: