Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50000038
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239529BDBM50239529(CHEMBL4072033)
Affinity DataIC50: 19nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239517BDBM50239517(CHEMBL4082508)
Affinity DataIC50: 25nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239516BDBM50239516(CHEMBL4060634)
Affinity DataIC50: 34nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239518BDBM50239518(CHEMBL4075978)
Affinity DataIC50: 36nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239530BDBM50239530(CHEMBL4101470)
Affinity DataIC50: 38nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239519BDBM50239519(CHEMBL4091797)
Affinity DataIC50: 41nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239514BDBM50239514(CHEMBL4098065)
Affinity DataIC50: 51nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239515BDBM50239515(CHEMBL4061657)
Affinity DataIC50: 65nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239511BDBM50239511(CHEMBL4065129)
Affinity DataIC50: 170nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50424783BDBM50424783(CHEMBL2315104)
Affinity DataIC50: 240nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239527BDBM50239527(CHEMBL4086571)
Affinity DataIC50: 250nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239524BDBM50239524(CHEMBL4092758)
Affinity DataIC50: 258nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239528BDBM50239528(CHEMBL4080038)
Affinity DataIC50: 260nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239512BDBM50239512(CHEMBL4069309)
Affinity DataIC50: 350nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239513BDBM50239513(CHEMBL4090348)
Affinity DataIC50: 502nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239521BDBM50239521(CHEMBL4084024)
Affinity DataIC50: 530nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371060BDBM50371060(CHEMBL226646)
Affinity DataIC50: 670nMAssay Description:Inhibition of SCD1 in human HepG2 cells assessed as ratio of cellular protein product over substrate after 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50424783BDBM50424783(CHEMBL2315104)
Affinity DataIC50: 750nMAssay Description:Inhibition of SCD1 in human HepG2 cells assessed as ratio of cellular protein product over substrate after 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239520BDBM50239520(CHEMBL4070933)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239531BDBM50239531(CHEMBL4062310)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304937BDBM50304937(N-phenethyl-6-(4-(2-(trifluoromethyl)benzoyl)piper...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239522BDBM50239522(CHEMBL4073664)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50424784BDBM50424784(CHEMBL2315103)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239526BDBM50239526(CHEMBL4085001)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239525BDBM50239525(CHEMBL4102948)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239533BDBM50239533(CHEMBL4078027)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239532BDBM50239532(CHEMBL4065076)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239523BDBM50239523(CHEMBL4100482)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239511BDBM50239511(CHEMBL4065129)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of SCD1 in human HepG2 cells assessed as ratio of cellular protein product over substrate after 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMed
TargetdCTP pyrophosphatase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241049BDBM50241049(CHEMBL463763 | Triptolide, 1 | triptolide)
Affinity DataIC50: 3.09E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)