Found 52 Enz. Inhib. hit(s) with all data for entry = 50002820 TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular calcium level pretreated ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular calcium level pretreated ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular calcium level pretreated ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular calcium level pretreated ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular calcium level pretreated ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced increase in intracellular calcium level pretreated f...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced increase in intracellular calcium level pretreated f...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular calcium level pretreated ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel, subfamily V, member 3(Rattus norvegicus)
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel, subfamily V, member 3(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.28E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.37E+4nMAssay Description:Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced increase in intracellular calcium level pretreated f...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.71E+4nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 3.97E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel, subfamily V, member 3(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel, subfamily V, member 3(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced increase in intracellular calcium level pretreated f...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel, subfamily V, member 3(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel, subfamily V, member 3(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced increase in intracellular calcium level pretreated f...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced increase in intracellular calcium level pretreated f...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular calcium level pret...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel, subfamily V, member 3(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 6.70E+3nMAssay Description:Agonist activity at rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 4.90E+3nMAssay Description:Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence ass...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 490nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 4.70E+3nMAssay Description:Agonist activity at rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 6.40E+3nMAssay Description:Agonist activity at rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 1.80E+4nMAssay Description:Agonist activity at rat TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 3.30E+3nMAssay Description:Agonist activity at rat TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 5.80E+3nMAssay Description:Agonist activity at rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 8.40E+3nMAssay Description:Agonist activity at rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 290nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
