Found 62 Enz. Inhib. hit(s) with all data for entry = 50010436 TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataKd: 13nMAssay Description:Binding affinity to wild-type human full length MELK (M1 to V651 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 45nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 641nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 354nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 26nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 8nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 9nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 203nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 123nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 105nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 73nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 1.25E+3nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 175nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 678nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 97nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 56nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 74nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 43nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 2.10E+3nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 990nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 4.66E+3nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 223nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 1.53E+3nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 59nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 46nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 383nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 1.34E+3nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Inhibition of human DYRK1A transfected in HEK293T cells co-transfected with Renilla plasmid, pGL3-NFAT and NFATc1 assessed as derepression of NFAT-de...More data for this Ligand-Target Pair
