Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 540nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 650nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 270nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 320nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 550nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 260nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 1.21E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 540nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 970nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 340nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 740nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 2.28E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 1.36E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 2.74E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 2.43E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 1.83E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 1.39E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 4.70E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 7.53E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 5.19E+3nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: 870nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair