Report error Found 157 Enz. Inhib. hit(s) with all data for entry = 50012834
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 0.600nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 0.600nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 0.840nMAssay Description:Binding affinity to human wild type PDGFRbeta (V582 to Y1009 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 1nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 1.10nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Binding affinity to human wild type PDGFRbeta (V582 to Y1009 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 1.30nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 1.30nMAssay Description:Binding affinity to human wild type PDGFRalpha (V575 to D1002 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 1.90nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 2.5nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 2.5nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 2.60nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 3.40nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 3.40nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 3.80nMAssay Description:Binding affinity to human wild type PDGFRbeta (V582 to Y1009 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 4.10nMAssay Description:Binding affinity to human wild type PDGFRbeta (V582 to Y1009 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 4.10nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 5.40nMAssay Description:Binding affinity to human wild type FLT3 (V592 to Y969 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 5.60nMAssay Description:Binding affinity to human wild type PDGFRbeta (V582 to Y1009 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 6.70nMAssay Description:Binding affinity to human wild type PDGFRbeta (V582 to Y1009 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 6.70nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of CSF1R in mouse NFS-60 cells assessed as reduction in CSF-induced cell proliferation after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of CSF1R in mouse NFS-60 cells assessed as reduction in CSF-induced cell proliferation after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 8.10nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 12nMAssay Description:Binding affinity to human wild type PDGFRalpha (V575 to D1002 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 12nMAssay Description:Binding affinity to human wild type PDGFRalpha (V575 to D1002 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of CSF1R in mouse NFS-60 cells assessed as reduction in CSF-induced cell proliferation after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
University of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair






















