Compile Data Set for Download or QSAR
maximum 50k data
Found 58 Enz. Inhib. hit(s) with all data for entry = 50017362
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50:  107nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50163745(4,40-(1E,10E)-2,20-(Isoxazole-3,5-diyl)bis(ethene-...)
Affinity DataIC50:  138nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50163748((E)-3,5-Bis[beta-(4-Hydroxy-3-methoxyphenyl)-ethen...)
Affinity DataIC50:  476nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50:  900nMAssay Description:Inhibition of amyloid beta (unknown origin) incubated for 7 days by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601423(CHEMBL5195740)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601422(CHEMBL5174150)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of amyloid beta 40 (unknown origin) assessed as disaggregation of fibrillar amyloid beta 40 incubated for 3 days by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601428(CHEMBL5175279)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601427(CHEMBL5176644)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601426(CHEMBL5200280)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601425(CHEMBL5189854)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601424(CHEMBL5209194)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50391730(CHEMBL258741)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of amyloid beta 42 transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601425(CHEMBL5189854)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601431(CHEMBL5183237)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601425(CHEMBL5189854)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601428(CHEMBL5175279)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601426(CHEMBL5200280)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50553256(CHEMBL258632 | N-(3-Nitrophenylpyrazole)Curcumin)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601427(CHEMBL5176644)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601426(CHEMBL5200280)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601425(CHEMBL5189854)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601431(CHEMBL5183237)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50163745(4,40-(1E,10E)-2,20-(Isoxazole-3,5-diyl)bis(ethene-...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601428(CHEMBL5175279)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50163745(4,40-(1E,10E)-2,20-(Isoxazole-3,5-diyl)bis(ethene-...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601427(CHEMBL5176644)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50163748((E)-3,5-Bis[beta-(4-Hydroxy-3-methoxyphenyl)-ethen...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601429(CHEMBL492807)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50163748((E)-3,5-Bis[beta-(4-Hydroxy-3-methoxyphenyl)-ethen...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601431(CHEMBL5183237)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601429(CHEMBL492807)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50391730(CHEMBL258741)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601424(CHEMBL5209194)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601429(CHEMBL492807)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601423(CHEMBL5195740)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50553256(CHEMBL258632 | N-(3-Nitrophenylpyrazole)Curcumin)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50391730(CHEMBL258741)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50553256(CHEMBL258632 | N-(3-Nitrophenylpyrazole)Curcumin)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601424(CHEMBL5209194)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601430(CHEMBL5205561)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601430(CHEMBL5205561)
Affinity DataIC50:  1.78E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601428(CHEMBL5175279)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50163748((E)-3,5-Bis[beta-(4-Hydroxy-3-methoxyphenyl)-ethen...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601424(CHEMBL5209194)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601427(CHEMBL5176644)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of tau (unknown origin) transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601422(CHEMBL5174150)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of amyloid beta 40 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50601422(CHEMBL5174150)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of amyloid beta 42 secretion transfected in human H4 cells incubated for 20 to 24 hrs by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Displayed 1 to 50 (of 58 total ) | Next | Last >>
Jump to: