Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50017784
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605031(CHEMBL5174789)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605030(CHEMBL5209131)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605036(CHEMBL5178803)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605042(CHEMBL5191709)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605037(CHEMBL5177167)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50274767(CHEMBL4125735)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605026(CHEMBL5206513)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605029(CHEMBL5187034)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605027(CHEMBL5199814)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605039(CHEMBL5187539)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM19187(CHEMBL396778 | (2S)-2-[({4-[(3-fluorophenyl)methox...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605040(CHEMBL5200705)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605033(CHEMBL5181534)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605038(CHEMBL5201892)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605041(CHEMBL5189255)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605043(CHEMBL5192912)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM10989((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605032(CHEMBL5188859)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605034(CHEMBL5173511)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605040(CHEMBL5200705)
Affinity DataIC50: 17nMAssay Description:Reversible inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605046(CHEMBL5191838)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605035(CHEMBL5175763)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605048(CHEMBL5193874)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605025(CHEMBL5193046)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605024(CHEMBL5183690)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605044(CHEMBL5190792)
Affinity DataIC50: 89nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605028(CHEMBL5197407)
Affinity DataIC50: 96nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605047(CHEMBL5195779)
Affinity DataIC50: 115nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605045(CHEMBL5182953)
Affinity DataIC50: 126nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605050(CHEMBL5177787)
Affinity DataIC50: 201nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605049(CHEMBL5171313)
Affinity DataIC50: 289nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605032(CHEMBL5188859)
Affinity DataKi:  350nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605028(CHEMBL5197407)
Affinity DataKi:  696nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605031(CHEMBL5174789)
Affinity DataKi:  740nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605030(CHEMBL5209131)
Affinity DataKi:  799nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605029(CHEMBL5187034)
Affinity DataKi:  838nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605034(CHEMBL5173511)
Affinity DataKi:  992nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605024(CHEMBL5183690)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605038(CHEMBL5201892)
Affinity DataKi:  1.23E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605037(CHEMBL5177167)
Affinity DataKi:  1.34E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605035(CHEMBL5175763)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50274767(CHEMBL4125735)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605036(CHEMBL5178803)
Affinity DataKi:  1.71E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605025(CHEMBL5193046)
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605033(CHEMBL5181534)
Affinity DataKi:  2.24E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605027(CHEMBL5199814)
Affinity DataKi:  3.02E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605040(CHEMBL5200705)
Affinity DataKi:  3.83E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605026(CHEMBL5206513)
Affinity DataKi:  3.31E+4nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605039(CHEMBL5187539)
Affinity DataKi:  4.03E+4nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50605040(CHEMBL5200705)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAO-A using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed