Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50018541
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human MAO-B assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate incubated for 20 mins by f...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human CK2 using RRRDDDSDDD as substrate in presence of [gamma-33P-ATP] incubated for 20 mins by beta-counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of porcine brain tubulin polymerization preincubated for 1 mins followed by GTP addition and measured for 60 mins at 1 min interval by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human MAO-AMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human MAO-BMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 39nMAssay Description:Binding affinity to human brain alpha-synuclein fibrilMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human MAO-B assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate incubated for 20 mins by f...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Universite Grenoble Alpes
Curated by ChEMBL
Universite Grenoble Alpes
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of AKT (unknown origin) by by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity to human brain homogenate amyloid beta by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate by Amplex-Red MAO assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human MAO-A assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate incubated for 20 mins by f...More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate by Amplex-Red MAO assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Universite Grenoble Alpes
Curated by ChEMBL
Universite Grenoble Alpes
Curated by ChEMBL
Affinity DataIC50: 207nMAssay Description:Inhibition of AKT (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Binding affinity to human brain homogenate amyloid beta by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human AchE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant GSK-3beta (unknown origin) using GS peptide as substrate in presence of ATP incubated for 1 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant human MAO-B assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate incubated for 20 mins by f...More data for this Ligand-Target Pair
Affinity DataKd: 390nMAssay Description:Binding affinity to human brain amyloid-beta fibrilMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant GSK-3beta (unknown origin) using GS peptide as substrate in presence of ATP incubated for 1 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
Universite Grenoble Alpes
Curated by ChEMBL
Universite Grenoble Alpes
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Binding affinity to PPARgamma (unknown origin) by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Inhibition of human HDAC4 in HeLa cells extract incubated for 5 mins followed by substrate addition and measured after 15 mins using Fluor-de-Lys as ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization preincubated for 1 mins followed by GTP addition and measured for 60 mins at 1 min interval by flu...More data for this Ligand-Target Pair
Affinity DataKi: 1.66E+3nMAssay Description:Inhibition of human HDAC8 in HeLa cells extract incubated for 5 mins followed by substrate addition and measured after 15 mins using Fluor-de-Lys as ...More data for this Ligand-Target Pair
Affinity DataKi: 1.66E+3nMAssay Description:Inhibition of human HDAC2 in HeLa cells extract incubated for 5 mins followed by substrate addition and measured after 15 mins using Fluor-de-Lys as ...More data for this Ligand-Target Pair
Affinity DataKi: 1.66E+3nMAssay Description:Inhibition of human HDAC7 in HeLa cells extract incubated for 5 mins followed by substrate addition and measured after 15 mins using Fluor-de-Lys as ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization preincubated for 30 mins followed by GTP addition and measured after 20 mins by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregation by ThT-based fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization preincubated for 1 mins followed by GTP addition and measured for 60 mins at 1 min interval by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Agaricus bisporus tyrosinase using L-DOPA as substrate incubated for 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.42E+3nMAssay Description:Antagonist activity at Gal4-RARalpha transfected in HEK293 cells assessed as atRA-induced RARalpha transactivation and measured after 6 hrs by Dual-L...More data for this Ligand-Target Pair
Affinity DataIC50: 7.56E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization preincubated for 1 mins followed by GTP addition and measured for 60 mins at 1 min interval by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) disaggregation by ThT-based fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.12E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 1 mins by spec...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of PIM1 (unknown origin) using poly-Glu-Tyr (4:1) as substrate in presence of [gamma-33P-ATP] incubated for 2 hrs by radiometric kinase as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of PIM1 (unknown origin) using poly-Glu-Tyr (4:1) as substrate in presence of [gamma-33P-ATP] incubated for 2 hrs by radiometric kinase as...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by spectrophotomet...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of recombinant human MAO-BMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of recombinant human MAO-A assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate incubated for 20 mins by f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAO-A assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate incubated for 20 mins by f...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of full length human PIM1 expressed in Escherichia coli BL21 (DE3) preincubated for 0.5 hrs followed by substrate addition and measured af...More data for this Ligand-Target Pair
3D Structure (crystal)