Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50017464
TargetCeramide glucosyltransferase(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602025(CHEMBL5181454)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602025(CHEMBL5181454)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602022(CHEMBL5197585)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602022(CHEMBL5197585)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602024(CHEMBL5178033)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602024(CHEMBL5178033)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602016(CHEMBL5193757)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602015(CHEMBL5198393)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602021(CHEMBL5185934)
Affinity DataIC50: 10nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602014(CHEMBL5182659)
Affinity DataIC50: 11nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602023(CHEMBL5183525)
Affinity DataIC50: 13nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602018(CHEMBL5186203)
Affinity DataIC50: 16nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602020(CHEMBL5185095)
Affinity DataIC50: 16nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602017(CHEMBL5186505)
Affinity DataIC50: 22nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602013(CHEMBL5200972)
Affinity DataIC50: 53nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602019(CHEMBL5192371)
Affinity DataIC50: 250nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed