Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50021600
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642423(CHEMBL5567321)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642414(CHEMBL5573550)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642431(CHEMBL5575019)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642413(CHEMBL5573404)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642427(CHEMBL5572601)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642432(CHEMBL5571201)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642418(CHEMBL5573275)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642419(CHEMBL5571531)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642422(CHEMBL5574515)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642421(CHEMBL5562669)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642406(CHEMBL5572804)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642424(CHEMBL5569810)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642398(CHEMBL5574814)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642425(CHEMBL5564489)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642399(CHEMBL5575248)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642428(CHEMBL5573875)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642396(CHEMBL5595938)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642420(CHEMBL5568847)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642401(CHEMBL5575526)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642403(CHEMBL5566696)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642410(CHEMBL5573153)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642426(CHEMBL5563495)
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642400(CHEMBL5564417)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642397(CHEMBL5570719)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642404(CHEMBL5575250)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642409(CHEMBL5592611)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642402(CHEMBL5572429)
Affinity DataIC50: 127nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642411(CHEMBL5589720)
Affinity DataIC50: 128nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642408(CHEMBL5572955)
Affinity DataIC50: 148nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642412(CHEMBL5579670)
Affinity DataIC50: 197nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642430(CHEMBL5562608)
Affinity DataIC50: 256nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642415(CHEMBL5590635)
Affinity DataIC50: 348nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642405(CHEMBL5572136)
Affinity DataIC50: 356nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642407(CHEMBL5572780)
Affinity DataIC50: 456nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642429(CHEMBL5568889)
Affinity DataIC50: 468nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642417(CHEMBL5590366)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642416(CHEMBL5583553)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642432(CHEMBL5571201)
Affinity DataIC50: 3.79E+4nMAssay Description:Inhibition of hERG by auto-patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed