Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50006230
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498024BDBM50498024(CHEMBL3326332)
Affinity DataIC50: 73nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498018BDBM50498018(CHEMBL3326331)
Affinity DataIC50: 97nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498026BDBM50498026(CHEMBL3326319)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498028BDBM50498028(CHEMBL3326325)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498030BDBM50498030(CHEMBL3326326)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108771BDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498027BDBM50498027(CHEMBL3326329)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498029BDBM50498029(CHEMBL3326323)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498023BDBM50498023(CHEMBL3326330)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498025BDBM50498025(CHEMBL3326324)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498020BDBM50498020(CHEMBL3326320)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498019BDBM50498019(CHEMBL3326322)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498022BDBM50498022(CHEMBL3326328)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498021BDBM50498021(CHEMBL3326327)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed