Compile Data Set for Download or QSAR
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Found 14 Enz. Inhib. hit(s) with all data for entry = 50006230
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498024(CHEMBL3326332)
Affinity DataIC50:  73nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498018(CHEMBL3326331)
Affinity DataIC50:  97nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498026(CHEMBL3326319)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498028(CHEMBL3326325)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498030(CHEMBL3326326)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50108771(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498029(CHEMBL3326323)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498027(CHEMBL3326329)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498025(CHEMBL3326324)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498022(CHEMBL3326328)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498021(CHEMBL3326327)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498020(CHEMBL3326320)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498019(CHEMBL3326322)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rattus norvegicus)
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498023(CHEMBL3326330)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed