Compile Data Set for Download or QSAR
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Found 44 Enz. Inhib. hit(s) with all data for entry = 50012854
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123395((S)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  0.75nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215((+/-)-3-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethy...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123397((S)-1-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-3...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50110814((+/-)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethy...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123396((S)-3-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  3nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM22167(1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)pip...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123388((R)-3-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123380((S)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  5.60nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123390((R)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  12nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123389((1S,2R)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-et...)
Affinity DataKi:  13nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123383(1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-pip...)
Affinity DataKi:  20nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123394((S)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  23nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123391((R)-1-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-3...)
Affinity DataKi:  25nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123386(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-ethy...)
Affinity DataKi:  34nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123377((1R,2S)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-et...)
Affinity DataKi:  36nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123385(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-prop...)
Affinity DataKi:  40nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123387((R)-1-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-p...)
Affinity DataKi:  44nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123393((S)-1-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-p...)
Affinity DataKi:  48nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123381(1-Allyl-4-{2-[bis-(4-fluoro-phenyl)-methoxy]-ethyl...)
Affinity DataKi:  65nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123382((R)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  76nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123396((S)-3-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  85nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083215((+/-)-3-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethy...)
Affinity DataKi:  117nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50110814((+/-)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethy...)
Affinity DataKi:  124nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataKi:  126nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123388((R)-3-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  135nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123384((R)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  140nMAssay Description:Binding affinity for dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123390((R)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  162nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123395((S)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  230nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123380((S)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  281nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123383(1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-pip...)
Affinity DataKi:  298nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123384((R)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  520nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123389((1S,2R)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-et...)
Affinity DataKi:  565nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123377((1R,2S)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-et...)
Affinity DataKi:  583nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123382((R)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  588nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM22167(1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)pip...)
Affinity DataKi:  623nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123385(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-prop...)
Affinity DataKi:  888nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123394((S)-1-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}...)
Affinity DataKi:  981nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123381(1-Allyl-4-{2-[bis-(4-fluoro-phenyl)-methoxy]-ethyl...)
Affinity DataKi:  1.65E+3nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123391((R)-1-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-3...)
Affinity DataKi:  1.83E+3nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123386(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-ethy...)
Affinity DataKi:  2.09E+3nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123397((S)-1-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-3...)
Affinity DataKi:  2.16E+3nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123393((S)-1-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-p...)
Affinity DataKi:  1.04E+4nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50123387((R)-1-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-p...)
Affinity DataKi:  1.29E+4nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed