Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50013144
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563067BDBM50563067(CHEMBL4743406)
Affinity DataEC50:  300nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563069BDBM50563069(CHEMBL4792581)
Affinity DataEC50:  400nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563055BDBM50563055(CHEMBL4744652)
Affinity DataEC50:  400nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563077BDBM50563077(CHEMBL4785311)
Affinity DataEC50:  500nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250187BDBM50250187(4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrr...)
Affinity DataEC50:  600nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563063BDBM50563063(CHEMBL4779926)
Affinity DataEC50:  700nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563082BDBM50563082(CHEMBL4761575)
Affinity DataEC50:  900nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563072BDBM50563072(CHEMBL4781954)
Affinity DataEC50:  900nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563073BDBM50563073(CHEMBL4750716)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563090BDBM50563090(CHEMBL4763653)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563064BDBM50563064(CHEMBL4798588)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563078BDBM50563078(CHEMBL4761954)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563068BDBM50563068(CHEMBL4751279)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563071BDBM50563071(CHEMBL4788544)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563057BDBM50563057(CHEMBL4753949)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563059BDBM50563059(CHEMBL4756274)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563054BDBM50563054(CHEMBL4745686)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563058BDBM50563058(CHEMBL4750788)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563060BDBM50563060(CHEMBL4763628)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250146BDBM50250146(Ethyl 5-(4-Chlorophenyl)-2-methyl-1-(4-sulfamoylph...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563056BDBM50563056(CHEMBL4796582)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50563054BDBM50563054(CHEMBL4745686)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at human alpha4beta2 nAChR stably expressed in HEK293 cells assessed as inhibition of acethylcholine-evoked currents by whole-cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250186BDBM50250186(4-(3-Acetyl-5-(4-chlorophenyl)-2-methyl-1H-pyrrol-...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563076BDBM50563076(CHEMBL4783972)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563065BDBM50563065(CHEMBL4799108)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563087BDBM50563087(CHEMBL4786198)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563074BDBM50563074(CHEMBL4780177)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563089BDBM50563089(CHEMBL4797167)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563088BDBM50563088(CHEMBL4747602)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563062BDBM50563062(CHEMBL4740661)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563080BDBM50563080(CHEMBL4744432)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563081BDBM50563081(CHEMBL4752316)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563083BDBM50563083(CHEMBL4740207)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563070BDBM50563070(CHEMBL4748327)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563061BDBM50563061(CHEMBL4788788)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563066BDBM50563066(CHEMBL4746562)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563054BDBM50563054(CHEMBL4745686)
Affinity DataEC50:  4.50E+3nMAssay Description:Positive allosteric modulation of recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in choline-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563084BDBM50563084(CHEMBL4745516)
Affinity DataEC50:  5.80E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563086BDBM50563086(CHEMBL4759542)
Affinity DataEC50:  5.90E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563077BDBM50563077(CHEMBL4785311)
Affinity DataEC50:  6.10E+3nMAssay Description:Positive allosteric modulation of recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in choline-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563075BDBM50563075(CHEMBL4791013)
Affinity DataEC50:  7.40E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563085BDBM50563085(CHEMBL4792222)
Affinity DataEC50:  7.40E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563079BDBM50563079(CHEMBL4793773)
Affinity DataEC50:  9.20E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed