Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50032253
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326249BDBM50326249(ethyl 5-(dimethylcarbamoyloxy)-1-methyl-1,4-dihydr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326250BDBM50326250((3aR,9bS)-1-methyl-1,2,3,3a,4,9b-hexahydrothiochro...)
Affinity DataIC50: 8.11nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10961BDBM10961(homotolserine | eseroline 2-ethylphenylcarbamate |...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10973BDBM10973((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326251BDBM50326251((3aR,9bS)-1-methyl-2,3,3a,4,5,9b-hexahydro-1H-benz...)
Affinity DataIC50: 17.3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10972BDBM10972((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10958BDBM10958((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 22.1nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10978BDBM10978((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326252BDBM50326252((3aR,9bS)-1-methyl-1,2,3,3a,4,9b-hexahydrochromeno...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326253BDBM50326253((R)-3-(1-(piperidin-1-yl)ethyl)phenyl dimethylcarb...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10959BDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326248BDBM50326248((3aS,8aS)-1,3a-dimethyl-1,2,3,3a,8,8a-hexahydropyr...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004000BDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 56.7nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326247BDBM50326247((3aS,8aS)-1,3a-dimethyl-1,2,3,3a,8,8a-hexahydropyr...)
Affinity DataIC50: 56.7nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10982BDBM10982(3,5-dimethylphenserine | (3aS,8aR)-1,3a,8-trimethy...)
Affinity DataIC50: 78nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326246BDBM50326246((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50: 94nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290389BDBM50290389(Methyl-carbamic acid 1-(3-fluoro-pyridin-4-ylamino...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10960BDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292573BDBM50292573((2-Ethyl-phenyl)-carbamic acid (3aS,8aS)-1,3a,8-tr...)
Affinity DataIC50: 125nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326265BDBM50326265(quilostigmine | CHEMBL1243298)
Affinity DataIC50: 148nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326264BDBM50326264((3aS,8aR)-8-benzyl-1,3a-dimethyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 161nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326263BDBM50326263((3aS,8aR)-8-benzyl-1,3a-dimethyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 245nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10985BDBM10985((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50: 285nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326262BDBM50326262((3aS,8aR)-8-formyl-1,3a-dimethyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326261BDBM50326261(Ethyl-carbamic acid 1-methyl-8,10,12-trioxa-tricyc...)
Affinity DataIC50: 388nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10980BDBM10980((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 690nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10988BDBM10988((3aS,8aR)-6-[(dimethylamino)methyl]-1,3a,8-trimeth...)
Affinity DataIC50: 780nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8961BDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326260BDBM50326260((3aS,8aR)-3a-methyl-1,2,3,3a,8,8a-hexahydropyrrolo...)
Affinity DataIC50: 830nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014112BDBM50014112(CHEMBL74257 | Methyl-carbamic acid 1-benzyl-3a,8-d...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326259BDBM50326259((3aS,8aR)-8-formyl-1,3a-dimethyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326258BDBM50326258(2-Chlorophenylcarbamic Acid 1-Benzyl-1,2,3,4-tetra...)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326257BDBM50326257((3aS,8aR)-1,8-dibenzyl-3a-methyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10620BDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326256BDBM50326256((4-Isopropyl-phenyl)-carbamic acid 1-methyl-8,10,1...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326255BDBM50326255((3aR,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50: 9.89E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326254BDBM50326254((3aS,8aR)-1,8-dibenzyl-3a-methyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 4.11E+4nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed