Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50039416
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343354BDBM50343354(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343355BDBM50343355(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343372BDBM50343372(Amino-4-(2,4-dichloro-6-phenethyloxyphenyl)-5,7-di...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343380BDBM50343380(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343370BDBM50343370(2-Amino-4-[2,4-dichloro-6-(4,4,4-trifluorobutoxy)p...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343386BDBM50343386(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343385BDBM50343385(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343356BDBM50343356(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343384BDBM50343384(4-(2-(2-(1H-pyrazol-1-yl)ethoxy)-4,6-dichloropheny...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343383BDBM50343383(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343378BDBM50343378(2-Amino-4-{2,4-dichloro-6-[2-(3,3-difluoro-azetidi...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343369BDBM50343369(2-Amino-4-[2,4-dichloro-6-(4,4,4-trifluorobutoxy)p...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343382BDBM50343382(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343368BDBM50343368(2-Amino-4-[2,4-dichloro-6-(4,4,4-trifluorobutoxy)p...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343366BDBM50343366(2-Amino-4-[2,4-dichloro-6-(4,4,4-trifluorobutoxy)p...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343373BDBM50343373(2-Amino-4-[2,4-dichloro-6-(2-pyridin-2-ylethoxy)ph...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343381BDBM50343381(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343367BDBM50343367(2-Amino-4-[2,4-dichloro-6-(4,4,4-trifluorobutoxy)p...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343374BDBM50343374(2-amino-N-cyclobutyl-4-(2,4-dichloro-6-(3-cyanopro...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343365BDBM50343365(4-[2,4-Dichloro-6-(4,4,4-trifluoro-butoxy)-phenyl]...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343371BDBM50343371(2-amino-N-cyclobutyl-4-(2,4-dichloro-6-propoxyphen...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343377BDBM50343377(2-Amino-4-[2,4-dichloro-6-(2-methoxyethoxy)phenyl]...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343364BDBM50343364(4-[2-Chloro-6-(4,4,4-trifluoro-butoxy)-phenyl]-6-m...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343376BDBM50343376(2-Amino-4-[2,4-dichloro-6-(3-hydroxypropoxy)phenyl...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343379BDBM50343379(2-Amino-4-[2,4-dichloro-6-(2-ethylamino-ethoxy)-ph...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343375BDBM50343375(2-Amino-4-[2,4-dichloro-6-(3-cyano-3,3-dimethylpro...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343359BDBM50343359(2-Amino-4-{2,4-dichloro-6-[2-(4-fluoropyrazol-1-yl...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343362BDBM50343362(4-(2-chloro-6-methoxyphenyl)-6-methylpyrimidin-2-a...)
Affinity DataKi:  700nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343357BDBM50343357(2-Amino-4-{2,4-dichloro-6-[2-(4-fluoropyrazol-1-yl...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343354BDBM50343354(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343360BDBM50343360(4-Chloro-6-(2-methoxyphenyl)-pyrimidin-2-ylamine |...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343358BDBM50343358(2-Amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)eth...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343363BDBM50343363(2-(2-amino-6-methylpyrimidin-4-yl)-3-chlorophenol ...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343355BDBM50343355(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343356BDBM50343356(2-Amino-4-[2,4-dichloro-6-(2-pyrazol-1-ylethoxy)ph...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343353BDBM50343353(2-Amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)eth...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343361BDBM50343361(4-(2-methoxyphenyl)-6-methylpyrimidin-2-amine | CH...)
Affinity DataKi:  8.30E+3nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50343365BDBM50343365(4-[2,4-Dichloro-6-(4,4,4-trifluoro-butoxy)-phenyl]...)
Affinity DataKi:  1.16E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343353BDBM50343353(2-Amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)eth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343353BDBM50343353(2-Amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)eth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343353BDBM50343353(2-Amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)eth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343353BDBM50343353(2-Amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)eth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343353BDBM50343353(2-Amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)eth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343353BDBM50343353(2-Amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)eth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343353BDBM50343353(2-Amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)eth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed