Compile Data Set for Download or QSAR
Report error Found 120 Enz. Inhib. hit(s) with all data for entry = 402
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1954BDBM1954(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 90nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1317BDBM1317(3-{[(4,7-dichloro-1,3-benzoxazol-2-yl)methyl]amino...)
Affinity DataIC50: 110nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1966BDBM1966(1-[(5-Methylsulfonaminoindol-2-yl)carbonyl]-4-[N-e...)
Affinity DataIC50: 130nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1967BDBM1967(1-[[5-[[(4-Methyl-1-piperazinyl)carbonyl]amino]ind...)
Affinity DataIC50: 140nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1969BDBM1969(N-{2-[(4-{ethyl[3-(propan-2-ylamino)pyridin-2-yl]a...)
Affinity DataIC50: 140nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1964BDBM1964(N-{2-[(4-{[3-(ethylamino)pyridin-2-yl](propyl)amin...)
Affinity DataIC50: 150nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1955BDBM1955(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 160nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1950BDBM1950({2-[(4-{methyl[3-(propan-2-ylamino)pyridin-2-yl]am...)
Affinity DataIC50: 170nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1969BDBM1969(N-{2-[(4-{ethyl[3-(propan-2-ylamino)pyridin-2-yl]a...)
Affinity DataIC50: 180nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1948BDBM1948(3-methyl-1-{2-[(4-{methyl[3-(propan-2-ylamino)pyri...)
Affinity DataIC50: 180nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 2661BDBM2661(4-methyl-N-{2-[(4-{[3-(propan-2-ylamino)pyridin-2-...)
Affinity DataIC50: 190nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1956BDBM1956(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 200nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 2668BDBM2668(1-[[5-[[(4-Methyl-1-piperazinyl)carbonyl]amino]ind...)
Affinity DataIC50: 210nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1954BDBM1954(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 210nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 2659BDBM2659(N-{2-[(4-{[3-(tert-butylamino)pyridin-2-yl](ethyl)...)
Affinity DataIC50: 220nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1958BDBM1958(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 230nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1945BDBM1945(2-N-[1-(1H-indol-2-ylcarbonyl)piperidin-4-yl]-2-N-...)
Affinity DataIC50: 230nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1968BDBM1968(N-{2-[(4-{ethyl[3-(ethylamino)pyridin-2-yl]amino}p...)
Affinity DataIC50: 240nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1957BDBM1957(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 240nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1967BDBM1967(1-[[5-[[(4-Methyl-1-piperazinyl)carbonyl]amino]ind...)
Affinity DataIC50: 240nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1957BDBM1957(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 240nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1956BDBM1956(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 250nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1962BDBM1962(N-{2-[(4-{ethyl[3-(ethylamino)pyridin-2-yl]amino}p...)
Affinity DataIC50: 260nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1944BDBM1944(BHAP deriv. | N-[2-({4-[3-(propan-2-ylamino)pyridi...)
Affinity DataIC50: 260nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1966BDBM1966(1-[(5-Methylsulfonaminoindol-2-yl)carbonyl]-4-[N-e...)
Affinity DataIC50: 280nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1954BDBM1954(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 280nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1946BDBM1946(2-{2-[2-({2-[(4-{methyl[3-(propan-2-ylamino)pyridi...)
Affinity DataIC50: 300nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1959BDBM1959(N-{2-[(4-{[3-(tert-butylamino)pyridin-2-yl](ethyl)...)
Affinity DataIC50: 320nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1434BDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 320nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1963BDBM1963(N-{2-[(4-{ethyl[3-(ethylamino)pyridin-2-yl]amino}p...)
Affinity DataIC50: 330nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1952BDBM1952(1-[[5-[(Methylsulfonyl)amino]indol-2-yl]carbonyl]-...)
Affinity DataIC50: 350nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 2663BDBM2663(N-{2-[(4-{[6-chloro-3-(propan-2-ylamino)pyridin-2-...)
Affinity DataIC50: 360nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1950BDBM1950({2-[(4-{methyl[3-(propan-2-ylamino)pyridin-2-yl]am...)
Affinity DataIC50: 370nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1955BDBM1955(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 370nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 2659BDBM2659(N-{2-[(4-{[3-(tert-butylamino)pyridin-2-yl](ethyl)...)
Affinity DataIC50: 370nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1970BDBM1970(N-{2-[(4-{ethyl[3-(propan-2-ylamino)pyridin-2-yl]a...)
Affinity DataIC50: 380nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1965BDBM1965(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 380nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1951BDBM1951(N-{2-[(4-{[3-(tert-butylamino)pyridin-2-yl](methyl...)
Affinity DataIC50: 390nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 2661BDBM2661(4-methyl-N-{2-[(4-{[3-(propan-2-ylamino)pyridin-2-...)
Affinity DataIC50: 400nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1956BDBM1956(1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...)
Affinity DataIC50: 400nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1962BDBM1962(N-{2-[(4-{ethyl[3-(ethylamino)pyridin-2-yl]amino}p...)
Affinity DataIC50: 400nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1946BDBM1946(2-{2-[2-({2-[(4-{methyl[3-(propan-2-ylamino)pyridi...)
Affinity DataIC50: 410nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1969BDBM1969(N-{2-[(4-{ethyl[3-(propan-2-ylamino)pyridin-2-yl]a...)
Affinity DataIC50: 410nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1968BDBM1968(N-{2-[(4-{ethyl[3-(ethylamino)pyridin-2-yl]amino}p...)
Affinity DataIC50: 440nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1966BDBM1966(1-[(5-Methylsulfonaminoindol-2-yl)carbonyl]-4-[N-e...)
Affinity DataIC50: 450nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1963BDBM1963(N-{2-[(4-{ethyl[3-(ethylamino)pyridin-2-yl]amino}p...)
Affinity DataIC50: 450nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1961BDBM1961(N-{2-[(4-{ethyl[3-(ethylamino)pyridin-2-yl]amino}p...)
Affinity DataIC50: 460nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 2665BDBM2665(N-{2-[(4-{ethyl[6-fluoro-3-(propan-2-ylamino)pyrid...)
Affinity DataIC50: 460nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1959BDBM1959(N-{2-[(4-{[3-(tert-butylamino)pyridin-2-yl](ethyl)...)
Affinity DataIC50: 460nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Upjohn

LigandChemical structure of BindingDB Monomer ID 1962BDBM1962(N-{2-[(4-{ethyl[3-(ethylamino)pyridin-2-yl]amino}p...)
Affinity DataIC50: 480nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
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