Compile Data Set for Download or QSAR
Report error Found 113 Enz. Inhib. hit(s) with all data for entry = 9229
TargetSphingosine 1-phosphate receptor 3(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataIC50: 0.400nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataIC50: 1.40nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataIC50: 1.40nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450754BDBM450754(US10676467, Compound TZ 35 110)
Affinity DataIC50: 2.63nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 5(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataIC50: 3.10nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 2(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 50158348BDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataIC50: 3.60nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450758BDBM450758(US10676467, Compound TZ 33 21)
Affinity DataIC50: 3.80nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450734BDBM450734(US10676467, Compound 8h)
Affinity DataIC50: 3.90nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450734BDBM450734(US10676467, Compound 8h)
Affinity DataIC50: 3.90nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450771BDBM450771(US10676467, Compound TZ 48 22)
Affinity DataIC50: 5.05nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450788BDBM450788(US10676467, Compound TZ 48 65)
Affinity DataIC50: 6.30nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450730BDBM450730(US10676467, Compound 8c | US10676467, Compound TZ ...)
Affinity DataIC50: 6.67nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450730BDBM450730(US10676467, Compound 8c | US10676467, Compound TZ ...)
Affinity DataIC50: 6.70nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450730BDBM450730(US10676467, Compound 8c | US10676467, Compound TZ ...)
Affinity DataIC50: 6.70nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450784BDBM450784(US10676467, Compound TZ 50 17)
Affinity DataIC50: 7.30nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450785BDBM450785(US10676467, Compound TZ 43 91)
Affinity DataIC50: 7.40nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 50063864BDBM50063864(CHEMBL3403619 | US10676467, Compound TZ 50 13)
Affinity DataIC50: 8.34nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 22211BDBM22211(1-({4-[5-(4-ethoxyphenyl)-1,2,4-oxadiazol-3-yl]phe...)
Affinity DataIC50: 8.53nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450770BDBM450770(US10676467, Compound TZ 43 113)
Affinity DataIC50: 9.65nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450753BDBM450753(US10676467, Compound TZ 35 115)
Affinity DataIC50: 9.94nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450765BDBM450765(US10676467, Compound TZ 43 73)
Affinity DataIC50: 13.2nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450739BDBM450739(US10676467, Compound 12a)
Affinity DataIC50: 14nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450739BDBM450739(US10676467, Compound 12a)
Affinity DataIC50: 14nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450776BDBM450776(US10676467, Compound TZ 43 153)
Affinity DataIC50: 14.7nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450740BDBM450740(US10676467, Compound 12b)
Affinity DataIC50: 15.4nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450729BDBM450729(US10676467, Compound 8b | US10676467, Compound TZ ...)
Affinity DataIC50: 15.4nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450729BDBM450729(US10676467, Compound 8b | US10676467, Compound TZ ...)
Affinity DataIC50: 15.4nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450740BDBM450740(US10676467, Compound 12b)
Affinity DataIC50: 15.4nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450781BDBM450781(US10676467, Compound TZ 48 24)
Affinity DataIC50: 18.4nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450735BDBM450735(US10676467, Compound 8i)
Affinity DataIC50: 19.2nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450736BDBM450736(US10676467, Compound 8k)
Affinity DataIC50: 23.8nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450775BDBM450775(US10676467, Compound TZ 43 151 )
Affinity DataIC50: 30.8nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450779BDBM450779(US10676467, Compound TZ 43 146)
Affinity DataIC50: 34.2nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450733BDBM450733(US10676467, Compound 8g)
Affinity DataIC50: 38nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450768BDBM450768(US10676467, Compound TZ 43 102)
Affinity DataIC50: 40nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450761BDBM450761(US10676467, Compound TZ 43 57)
Affinity DataIC50: 41.7nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450774BDBM450774(US10676467, Compound TZ 43 143)
Affinity DataIC50: 45.4nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450755BDBM450755(US10676467, Compound TZ 35 124)
Affinity DataIC50: 45.4nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450732BDBM450732(US10676467, Compound 8f)
Affinity DataIC50: 48.2nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450763BDBM450763(US10676467, Compound TZ 43 18)
Affinity DataIC50: 53.7nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450731BDBM450731(US10676467, Compound 8e)
Affinity DataIC50: 59.6nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450766BDBM450766(US10676467, Compound TZ 43 77)
Affinity DataIC50: 67nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450772BDBM450772(US10676467, Compound TZ 43 117)
Affinity DataIC50: 72.9nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450759BDBM450759(US10676467, Compound TZ 33 37)
Affinity DataIC50: 75.3nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450743BDBM450743(US10676467, Compound 12f)
Affinity DataIC50: 75.6nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450762BDBM450762(US10676467, Compound TZ 35 139)
Affinity DataIC50: 76.4nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450737BDBM450737(US10676467, Compound 10a)
Affinity DataIC50: 87.2nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450778BDBM450778(US10676467, Compound TZ 43 158)
Affinity DataIC50: 87.2nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450749BDBM450749(US10676467, Compound TZ 35 73)
Affinity DataIC50: 92.7nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

US Patent
LigandChemical structure of BindingDB Monomer ID 450750BDBM450750(US10676467, Compound TZ 31 120)
Affinity DataIC50: 95.7nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

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