Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50007658
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066086(1N-{6-[1'-[2-(1-amino-1-methylethylcarboxamido)-3-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory concentration of the compound (biotinylated probe) is evaluated for [35S]- MK-0677 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066092(3N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  68nMAssay Description:Antagonistic activity against Oxytocin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066084(3N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  130nMAssay Description:Antagonistic activity against Oxytocin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066101(CHEMBL322912 | Piperidine-4-carboxylic acid {(R)-1...)
Affinity DataEC50:  0.340nMAssay Description:Compound was evaluated for GH release for effect on human GH secretagogue receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049478(1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-di...)
Affinity DataKd:  0.140nMAssay Description:Compound was evaluated for binding affinity using [35S]-MK-0677 (800-1100 Ci/mmol), as radioligand having specific high activityMore data for this Ligand-Target Pair