Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 539
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM277313(1'-phenethyl-2,4-dihydro-1H-spiro[isoquinoline-3,4...)
Affinity DataKi: <100nMpH: 8.0Assay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM277314(1'-benzyl-2,4-dihydro-1H-spiro[isoquinoline-3,4'-p...)
Affinity DataKi: <100nMpH: 8.0Assay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM277315(1'-phenethyl-2,4-dihydro-1H-spiro[isoquinoline-3,4...)
Affinity DataKi: <100nMpH: 8.0Assay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM277316(1'-benzyl-2,4-dihydro-1H-spiro[isoquinoline-3,4'-p...)
Affinity DataKi: <100nMpH: 8.0Assay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM277318(1'-benzyl-2-methyl-2,4-dihydro-1H-spiro[isoquinoli...)
Affinity DataKi: <100nMpH: 8.0Assay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM277317(1-(1'-phenethyl-1H-spiro[isoquinoline-3,4'-piperid...)
Affinity DataKi: <500nMpH: 8.0Assay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM277319(4-(2-(2-methyl-2,4-dihydro-1H-spiro[isoquinoline-3...)
Affinity DataKi: <500nMpH: 8.0Assay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent