Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 9018
TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435718BDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)
Affinity DataIC50: 0.0400nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435718BDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)
Affinity DataIC50: 0.670nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435718BDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)
Affinity DataIC50: 0.75nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435722BDBM435722(US10570155, Compound 31III)
Affinity DataIC50: 0.980nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435721BDBM435721(US10570155, Compound 25III | US11332479, Compound ...)
Affinity DataIC50: 1nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435711BDBM435711(US10570155, Compound 1II | US11332479, Compound 1I...)
Affinity DataIC50: 1.85nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50289149BDBM50289149(GW305074X | US10570155, GW5074 | GW5074 | US113324...)
Affinity DataIC50: 2.58nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435711BDBM435711(US10570155, Compound 1II | US11332479, Compound 1I...)
Affinity DataIC50: 2.95nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50289149BDBM50289149(GW305074X | US10570155, GW5074 | GW5074 | US113324...)
Affinity DataIC50: 2.96nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435711BDBM435711(US10570155, Compound 1II | US11332479, Compound 1I...)
Affinity DataIC50: 3.23nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435722BDBM435722(US10570155, Compound 31III)
Affinity DataIC50: 4.19nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435721BDBM435721(US10570155, Compound 25III | US11332479, Compound ...)
Affinity DataIC50: 5.70nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435722BDBM435722(US10570155, Compound 31III)
Affinity DataIC50: 7.83nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50289149BDBM50289149(GW305074X | US10570155, GW5074 | GW5074 | US113324...)
Affinity DataIC50: 8.52nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50396483BDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 31nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50396483BDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 48nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435719BDBM435719(US10570155, Compound 2III | US11332479, Compound 2...)
Affinity DataIC50: 77nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435720BDBM435720(US10570155, Compound 8III | US11332479, Compound 8...)
Affinity DataIC50: 98nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 50396483BDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 100nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435719BDBM435719(US10570155, Compound 2III | US11332479, Compound 2...)
Affinity DataIC50: 459nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 435720BDBM435720(US10570155, Compound 8III | US11332479, Compound 8...)
Affinity DataIC50: 687nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent