Compile Data Set for Download or QSAR
Report error Found 487 Enz. Inhib. hit(s) with all data for entry = 10298
TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525710BDBM525710(US11174252, Compound 4)
Affinity DataIC50: 0.100nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525562BDBM525562(US11174252, Compound 1)
Affinity DataIC50: 0.200nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525562BDBM525562(US11174252, Compound 1)
Affinity DataIC50: 0.200nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525763BDBM525763(US11174252, Compound 450)
Affinity DataIC50: 0.300nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525786BDBM525786(US11174252, Compound 474)
Affinity DataIC50: 0.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525763BDBM525763(US11174252, Compound 450)
Affinity DataIC50: 0.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525771BDBM525771(US11174252, Compound 458)
Affinity DataIC50: 0.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525754BDBM525754(US11174252, Compound 441)
Affinity DataIC50: 0.600nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525710BDBM525710(US11174252, Compound 4)
Affinity DataIC50: 0.700nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525717BDBM525717(US11174252, Compound 12)
Affinity DataIC50: 0.700nMAssay Description:CDK5 (p25): IC50 values of compounds against CDK5 (p25) were determined by Z′-LYTE™. These screening assays were performed at Invitrogen L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525762BDBM525762(US11174252, Compound 449)
Affinity DataIC50: 0.900nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525724BDBM525724(US11174252, Compound 19)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525755BDBM525755(US11174252, Compound 442)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525819BDBM525819(US11174252, Compound 512)
Affinity DataIC50: 1nMAssay Description:CDK5 (p25): IC50 values of compounds against CDK5 (p25) were determined by Z′-LYTE™. These screening assays were performed at Invitrogen L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525732BDBM525732(US11174252, Compound 27)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 525820BDBM525820(US11174252, Compound 513)
Affinity DataIC50: 1nMAssay Description:CDK1 (cyclin B): IC50 values of compounds against CDK1 (cyclin B) were determined by Z′-LYTE™. These screening assays were performed at In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 525769BDBM525769(US11174252, Compound 456)
Affinity DataIC50: 1nMAssay Description:CDK1 (cyclin B): IC50 values of compounds against CDK1 (cyclin B) were determined by Z′-LYTE™. These screening assays were performed at In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525733BDBM525733(US11174252, Compound 28)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525769BDBM525769(US11174252, Compound 456)
Affinity DataIC50: 1nMAssay Description:CDK5 (p25): IC50 values of compounds against CDK5 (p25) were determined by Z′-LYTE™. These screening assays were performed at Invitrogen L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525822BDBM525822(US11174252, Compound 516)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525734BDBM525734(US11174252, Compound 29)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525735BDBM525735(US11174252, Compound 30)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 525825BDBM525825(US11174252, Compound 520)
Affinity DataIC50: 1nMAssay Description:CDK1 (cyclin B): IC50 values of compounds against CDK1 (cyclin B) were determined by Z′-LYTE™. These screening assays were performed at In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525825BDBM525825(US11174252, Compound 520)
Affinity DataIC50: 1nMAssay Description:CDK5 (p25): IC50 values of compounds against CDK5 (p25) were determined by Z′-LYTE™. These screening assays were performed at Invitrogen L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525721BDBM525721(US11174252, Compound 16)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525721BDBM525721(US11174252, Compound 16)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525738BDBM525738(US11174252, Compound 33)
Affinity DataIC50: 1nMAssay Description:CDK5 (p25): IC50 values of compounds against CDK5 (p25) were determined by Z′-LYTE™. These screening assays were performed at Invitrogen L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525754BDBM525754(US11174252, Compound 441)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525806BDBM525806(US11174252, Compound 498)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525819BDBM525819(US11174252, Compound 512)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525724BDBM525724(US11174252, Compound 19)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525792BDBM525792(US11174252, Compound 481)
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525762BDBM525762(US11174252, Compound 449)
Affinity DataIC50: 1.10nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525760BDBM525760(US11174252, Compound 447)
Affinity DataIC50: 1.10nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 525815BDBM525815(US11174252, Compound 507)
Affinity DataIC50: 1.30nMAssay Description:CDK1 (cyclin B): IC50 values of compounds against CDK1 (cyclin B) were determined by Z′-LYTE™. These screening assays were performed at In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525749BDBM525749(US11174252, Compound 436)
Affinity DataIC50: 1.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525768BDBM525768(US11174252, Compound 455)
Affinity DataIC50: 1.5nMAssay Description:FMS: IC50 values of compounds against FMS kinase were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen (Life Technologies Grand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525738BDBM525738(US11174252, Compound 33)
Affinity DataIC50: 1.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525738BDBM525738(US11174252, Compound 33)
Affinity DataIC50: 1.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525775BDBM525775(US11174252, Compound 463)
Affinity DataIC50: 1.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525743BDBM525743(US11174252, Compound 38)
Affinity DataIC50: 1.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525823BDBM525823(US11174252, Compound 517)
Affinity DataIC50: 1.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525718BDBM525718(US11174252, Compound 13)
Affinity DataIC50: 1.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525757BDBM525757(US11174252, Compound 444)
Affinity DataIC50: 1.60nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525760BDBM525760(US11174252, Compound 447)
Affinity DataIC50: 1.60nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 525819BDBM525819(US11174252, Compound 512)
Affinity DataIC50: 2nMAssay Description:CDK1 (cyclin B): IC50 values of compounds against CDK1 (cyclin B) were determined by Z′-LYTE™. These screening assays were performed at In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525820BDBM525820(US11174252, Compound 513)
Affinity DataIC50: 2nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525727BDBM525727(US11174252, Compound 22)
Affinity DataIC50: 2nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525727BDBM525727(US11174252, Compound 22)
Affinity DataIC50: 2nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 525801BDBM525801(US11174252, Compound 490)
Affinity DataIC50: 2nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

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