Compile Data Set for Download or QSAR
Report error Found 218 Enz. Inhib. hit(s) with all data for entry = 10694
TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547894(CHEMBL4760292 | US11377438, Example 172)
Affinity DataIC50: 0.300nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547896(CHEMBL4777598 | US11377438, Example 184)
Affinity DataIC50: 0.5nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560005(US11377438, Example 53)
Affinity DataIC50: 0.800nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547885(CHEMBL4781110 | US11377438, Example 18)
Affinity DataIC50: 0.900nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547890(CHEMBL4745699 | US11377438, Example 46)
Affinity DataIC50: 1nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560161(US11377438, Example 201)
Affinity DataIC50: 1.30nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560001(US11377438, Example 49)
Affinity DataIC50: 1.40nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560008(US11377438, Example 55)
Affinity DataIC50: 1.40nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560073(US11377438, Example 115)
Affinity DataIC50: 1.60nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547886(CHEMBL4764433 | US11377438, Example 19)
Affinity DataIC50: 1.60nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560162(US11377438, Example 202)
Affinity DataIC50: 1.90nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560089(US11377438, Example 131)
Affinity DataIC50: 2nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM559975(US11377438, Example 24)
Affinity DataIC50: 2.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560006(US11377438, Example 54)
Affinity DataIC50: 2.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560124(US11377438, Example 164 | US11377438, Example 165)
Affinity DataIC50: 2.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560178(US11377438, Example 218)
Affinity DataIC50: 2.40nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547889(CHEMBL4743638 | US11377438, Example 23)
Affinity DataIC50: 2.60nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547895(CHEMBL4751356 | US11377438, Example 177)
Affinity DataIC50: 2.80nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560004(US11377438, Example 52)
Affinity DataIC50: 2.80nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560078(US11377438, Example 120)
Affinity DataIC50: 2.90nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547888(CHEMBL4748189 | US11377438, Example 22)
Affinity DataIC50: 3nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547884(CHEMBL4778738 | US11377438, Example 17)
Affinity DataIC50: 3.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560177(US11377438, Example 217)
Affinity DataIC50: 3.20nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560124(US11377438, Example 164 | US11377438, Example 165)
Affinity DataIC50: 3.30nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560145(US11377438, Example 185)
Affinity DataIC50: 3.80nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM559999(US11377438, Example 47 | US11377438, Example 48)
Affinity DataIC50: 3.90nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547891(CHEMBL4777784 | US11377438, Example 101)
Affinity DataIC50: 3.90nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM559982(US11377438, Example 30)
Affinity DataIC50: 4nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM559992(US11377438, Example 40)
Affinity DataIC50: 4.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560134(US11377438, Example 174)
Affinity DataIC50: 4.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM559983(US11377438, Example 31)
Affinity DataIC50: 4.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547881(CHEMBL4796719 | US11377438, Example 13)
Affinity DataIC50: 4.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM559984(US11377438, Example 32)
Affinity DataIC50: 4.30nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547887(CHEMBL4759995 | US11377438, Example 21)
Affinity DataIC50: 4.5nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM559993(US11377438, Example 41)
Affinity DataIC50: 5.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547892(CHEMBL4788313 | US11377438, Example 132)
Affinity DataIC50: 5.30nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM559977(US11377438, Example 25)
Affinity DataIC50: 5.40nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547893(CHEMBL4752525 | US11377438, Example 138)
Affinity DataIC50: 5.80nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560148(US11377438, Example 188)
Affinity DataIC50: 5.90nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547882(CHEMBL4753100 | US11377438, Example 15)
Affinity DataIC50: 6.5nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560003(US11377438, Example 51)
Affinity DataIC50: 6.60nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560175(US11377438, Example 215)
Affinity DataIC50: 6.60nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560129(US11377438, Example 169)
Affinity DataIC50: 6.90nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560009(US11377438, Example 56)
Affinity DataIC50: 9.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560131(US11377438, Example 171)
Affinity DataIC50: 9.20nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560120(US11377438, Example 160 | US11377438, Example 161)
Affinity DataIC50: 9.20nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560011(US11377438, Example 58)
Affinity DataIC50: 10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM560122(US11377438, Example 162 | US11377438, Example 163)
Affinity DataIC50: 10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50547883(CHEMBL4763229 | US11377438, Example 16)
Affinity DataIC50: 12nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM559999(US11377438, Example 47 | US11377438, Example 48)
Affinity DataIC50: 12nMAssay Description:The following buffers were used for the Qube recordings: External buffer for Nav1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent

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