Compile Data Set for Download or QSAR
Report error Found 404 Enz. Inhib. hit(s) with all data for entry = 13467
TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 50069989BDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 3nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 50398609BDBM50398609(CHEMBL2141296 | MLN2238 | Ixazomib | NINLARO | IXA...)
Affinity DataIC50: 4nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetProteasome subunit beta type-1(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 50398609BDBM50398609(CHEMBL2141296 | MLN2238 | Ixazomib | NINLARO | IXA...)
Affinity DataIC50: 7nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795700BDBM795700(((1R)-1-(5-benzyl-3-((1-isopropyl-1H-indol-5-carbo...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795699BDBM795699(((1R)-1-(5-((1H-pyrazol-1-yl)methyl)-3-((isoquinol...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795866BDBM795866(((1R)-1-(5-benzyl-3-((2,5-dichlorobenzamido)methyl...)
Affinity DataIC50: 10nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795698BDBM795698(((1R)-1-(3-((1H-indol-4-carboxamido)methyl)-5-benz...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795697BDBM795697(((1R)-1-(3-((isoquinolin-1-carboxamido)methyl)-5-(...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795865BDBM795865(((1R)-1-(3-(benzamidomethyl)-5-benzyl-4,5-dihydroi...)
Affinity DataIC50: 10nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795703BDBM795703(((1R)-1-(5-benzyl-3-((imidazo[1,2-a]pyridin-8-carb...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795702BDBM795702(((1R)-1-(5-(hydroxy(phenyl)methyl)-3-((isoquinolin...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795701BDBM795701(((1R)-1-(5-benzyl-3-((2,4-dimethylthiazol-5-carbox...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795704BDBM795704(((1R)-1-(5-benzyl-3-((2-methylimidazo[1,2-a]pyridi...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795706BDBM795706(((1R)-1-(3-((imidazo[1,2-a]pyridin-8-carboxamido)m...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795707BDBM795707(((1R)-1-(3-((isoquinolin-1-carboxamido)methyl)-5-(...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795705BDBM795705(((1R)-1-(5-benzyl-3-((1-isopropyl-1H-indol-4-carbo...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795709BDBM795709(((1R)-1-(5-benzyl-3-((1-methyl-1H-indol-4-carboxam...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795708BDBM795708(((1R)-1-(3-((isoquinolin-1-carboxamido)methyl)-5-(...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795710BDBM795710(((1R)-1-(5-benzyl-3-((2-methylimidazo[1,2-a]pyridi...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were tested for ROR gamma inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795799BDBM795799(((1R)-1-(5-benzyl-3-((1-isopropyl-3-(pyridin-3-yl)...)
Affinity DataIC50: 10nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795800BDBM795800(((1R)-1-(5-benzyl-3-((1-isopropyl-3-(pyridin-4-yl)...)
Affinity DataIC50: 10nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795801BDBM795801(((1R)-1-(3-((1-isopropyl-3-phenyl-1H-pyrazol-5-car...)
Affinity DataIC50: 10nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795802BDBM795802(((1R)-1-(3-((3-(tert-butyl)-1-isopropyl-1H-pyrazol...)
Affinity DataIC50: 10nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795796BDBM795796(((1R)-1-(5-(3-chlorobenzyl)-3-((1-isopropyl-3-meth...)
Affinity DataIC50: 10nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795798BDBM795798(((1R)-1-(5-benzyl-3-((1,3-diisopropyl-1H-pyrazol-5...)
Affinity DataIC50: 10nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795794BDBM795794(((1R)-1-(5-(3-chlorobenzyl)-3-((5-isopropylisoxazo...)
Affinity DataIC50: 10nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795795BDBM795795(((1R)-1-(5-benzyl-3-((3-(tert-butyl)-1-isopropyl-1...)
Affinity DataIC50: 10nMAssay Description:TNF-α can induce necroptosis in Jurkat cells (human T lymphocytes) when FADD was deleted. This model was used to screen various libraries of che...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795712BDBM795712(((1R)-1-(3-((2,4-dimethylthiazol-5-carboxamido)met...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795711BDBM795711(((1R)-1-(5-benzyl-3-((3-chloro-2-methylimidazo[1,2...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795716BDBM795716(((1R)-1-(5-benzyl-3-((S)-1-(isoquinolin-1-carboxam...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795715BDBM795715(((1R)-1-(5-benzyl-3-((quinolin-8-sulfonamido)methy...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795713BDBM795713(((1R)-1-(5-benzyl-3-((3-chloroimidazo[1,2-a]pyridi...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795714BDBM795714(((1R)-1-(5-benzyl-3-(((2,5-dichlorophenyl)sulfonam...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795723BDBM795723(((1R)-1-(5-benzyl-3-((S)-1-(isoquinolin-1-carboxam...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795722BDBM795722([(1R)-1-[[5-benzyl-3-[[(5-methylpyrazin-2-carbonyl...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795720BDBM795720(((1R)-1-(5-((1H-pyrazol-1-yl)methyl)-3-((imidazo[1...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795721BDBM795721(((1R)-1-(3-((imidazo[1,2-a]pyridin-8-carboxamido)m...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795728BDBM795728([(1R)-1-[[5-benzyl-3-[1-(isoquinolin-1-carbonylami...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795725BDBM795725(((1R)-1-(3-((isoquinolin-1-carboxamido)methyl)-5-(...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795724BDBM795724(((1R)-1-(5-benzyl-3-((R)-1-(isoquinolin-1-carboxam...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795734BDBM795734(((1R)-1-(5-benzyl-3-((2-chloro-4,5-difluorobenzami...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795732BDBM795732(((1R)-1-(3-((3-aminopyrazin-2-carboxamido)methyl)-...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795731BDBM795731(((1R)-1-(5-benzyl-3-((6-methylpicolinamido)methyl)...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795730BDBM795730(((1R)-1-(5-benzyl-3-((3-methylpicolinamido)methyl)...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795741BDBM795741(((1R)-1-(5-(2-fluorobenzyl)-3-((isoquinolin-1-carb...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795738BDBM795738(((1R)-1-(3-((isoquinolin-1-carboxamido)methyl)-5-(...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795735BDBM795735(((1R)-1-(5-benzyl-3-((2-chloro-5-fluoronicotinamid...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795736BDBM795736(((1R)-1-(5-benzyl-3-((cinnolin-4-carboxamido)methy...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795748BDBM795748(((1R)-1-(5-(3-chlorobenzyl)-3-((imidazo[1,2-a]pyri...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 795745BDBM795745(((1R)-1-(5-(2,6-difluorobenzyl)-3-((isoquinolin-1-...)
Affinity DataIC50: 10nMAssay Description:Compounds described herein were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanoluc lucif...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

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