Compile Data Set for Download or QSAR
Report error Found 103 Enz. Inhib. hit(s) with all data for entry = 11635
TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 46246BDBM46246(4-[(5Z)-5-[[5-(1,3-benzothiazol-2-yl)furan-2-yl]me...)
Affinity DataIC50: 1.48E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635616BDBM635616(US20230364057, Compound 178)
Affinity DataIC50: 1.56E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635549BDBM635549(US20230364057, Compound 9)
Affinity DataIC50: 1.69E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 46319BDBM46319(3-[(5Z)-5-[[5-(1,3-benzothiazol-2-yl)furan-2-yl]me...)
Affinity DataIC50: 1.74E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 282BDBM282(Coumarin-Based, DNA Gyrase Inhibitor | (3R,4S,5R,6...)
Affinity DataIC50: 1.85E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 114259BDBM114259(MLS000777053 | 3-{5-[3-Oxo-benzo[4,5]imidazo[2,1-b...)
Affinity DataIC50: 1.87E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 58428BDBM58428(SMR000558865 | 2-[(5E)-5-[[5-(3-chlorophenyl)-2-fu...)
Affinity DataIC50: 2.00E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 54768BDBM54768(2-[3-[2-hydroxyethyl(dimethyl)azaniumyl]propanoyla...)
Affinity DataIC50: 2.18E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 21221BDBM21221(2-Cl-IB-MECA | CHEMBL431733 | C-IBzA-MU | 2-chloro...)
Affinity DataIC50: 2.53E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 50542241BDBM50542241(E127 | ERYTHROSINE | US20230364057, Compound 253)
Affinity DataIC50: 3.13E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635601BDBM635601(US20230364057, Compound 154)
Affinity DataIC50: 3.13E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 51271BDBM51271(SMR000415473 | MLS000778679 | (9-Methylsulfanyl-4-...)
Affinity DataIC50: 3.55E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 51784BDBM51784(MLS001165400 | 3-[3-(4-bromophenyl)-5,9-dimethyl-7...)
Affinity DataIC50: 4.28E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 50056938BDBM50056938(NSC-66209 | cid_72721 | CHEMBL175266 | 2,6,7-Trihy...)
Affinity DataIC50: 5.28E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635610BDBM635610(US20230364057, Compound 165)
Affinity DataIC50: 6.25E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635607BDBM635607(US20230364057, Compound 159)
Affinity DataIC50: 6.25E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 50723BDBM50723(6-{5-[1-[5-(4-Chloro-phenyl)-furan-2-yl]-meth-(E)-...)
Affinity DataIC50: 7.42E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635592BDBM635592(US20230364057, Compound 73)
Affinity DataIC50: 7.86E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635619BDBM635619(US20230364057, Compound 192)
Affinity DataIC50: 8.00E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635604BDBM635604(US20230364057, Compound 157)
Affinity DataIC50: 1.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 58376BDBM58376(3-[3-(4-chlorophenyl)-5-methyl-7-oxidanylidene-fur...)
Affinity DataIC50: 1.06E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635577BDBM635577(US20230364057, Compound 46)
Affinity DataIC50: 1.12E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 58639BDBM58639(cid_1329105 | 4-[(3-methoxynaphthalene-2-carbonyl)...)
Affinity DataIC50: 1.24E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635560BDBM635560(US20230364057, Compound 155)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635548BDBM635548(US20230364057, Compound 108)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635588BDBM635588(US20230364057, Compound 184)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635584BDBM635584(US20230364057, Compound 180)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635572BDBM635572(US20230364057, Compound 169)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 53210BDBM53210(3-[[4-(3-hydroxy-3-oxopropylamino)-9,10-bis(oxidan...)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635568BDBM635568(US20230364057, Compound 163)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635556BDBM635556(US20230364057, Compound 149)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 100207BDBM100207(cid_2291702 | (5E)-3-(3-chlorophenyl)-5-[[2,5-dime...)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 52412BDBM52412(1,3-dimethyl-5-[(5-phenylsulfanylfuran-2-yl)methyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635552BDBM635552(US20230364057, Compound 135)
Affinity DataIC50: 2.00E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635547BDBM635547(US20230364057, Compound 4)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635575BDBM635575(US20230364057, Compound 29)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635600BDBM635600(US20230364057, Compound 212)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635571BDBM635571(US20230364057, Compound 24)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 54422BDBM54422(4-(4-bromophenyl)-2-[(3,4,5-trimethoxybenzoyl)amin...)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635579BDBM635579(US20230364057, Compound 35)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635555BDBM635555(US20230364057, Compound 12)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 81278BDBM81278(MLS003115156 | cid_313614 | 4-(4-methylphenyl)sulf...)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 61719BDBM61719(SMR000370088 | cid_4386631 | MLS000759946 | 2-[5-e...)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635603BDBM635603(US20230364057, Compound 215)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635587BDBM635587(US20230364057, Compound 102)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 115153BDBM115153(SMR001566849 | MLS002703041 | Variamycin | cid_999...)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 34882BDBM34882(2-chloro-5-[4-[3-(2-furyl)-2-propenylidene]-5-oxo-...)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635559BDBM635559(US20230364057, Compound 18)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635609BDBM635609(US20230364057, Compound 224)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandChemical structure of BindingDB Monomer ID 635567BDBM635567(US20230364057, Compound 23)
Affinity DataIC50: 3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

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