Compile Data Set for Download or QSAR
Report error Found 109 Enz. Inhib. hit(s) with all data for entry = 12191
TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479502BDBM479502(ML300-based SC inhibitor 41 | US20240239772, Compo...)
Affinity DataIC50: 19nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685237BDBM685237(US20240239772, Compound 72 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 52nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685252BDBM685252(US20240239772, Compound 87 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 57nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685289BDBM685289(US20240239772, Compound 124 | N-[4-(aminomethyl)ph...)
Affinity DataIC50: 59nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479482BDBM479482(ML300-based SC inhibitor 21 | US20240239772, Compo...)
Affinity DataIC50: 60nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685240BDBM685240(US20240239772, Compound 75 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 62nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479502BDBM479502(ML300-based SC inhibitor 41 | US20240239772, Compo...)
Affinity DataIC50: 68nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685276BDBM685276(US20240239772, Compound 111 | 2-(benzotriazol-1-yl...)
Affinity DataIC50: 69nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479492BDBM479492(ML300-based SC inhibitor 31 | US20240239772, Compo...)
Affinity DataIC50: 74nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685248BDBM685248(US20240239772, Compound 83 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 76nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685283BDBM685283(US20240239772, Compound 118 | N-[4-(azetidin-3-yl)...)
Affinity DataIC50: 78nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685250BDBM685250(US20240239772, Compound 85 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 89nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685243BDBM685243(US20240239772, Compound 78 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 95nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685238BDBM685238(US20240239772, Compound 73 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 100nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685286BDBM685286(US20240239772, Compound 121 | N-[4-(azetidin-3-yl)...)
Affinity DataIC50: 100nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479480BDBM479480(ML300-based SC inhibitor 19 | US20240239772, Compo...)
Affinity DataIC50: 110nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479480BDBM479480(ML300-based SC inhibitor 19 | US20240239772, Compo...)
Affinity DataIC50: 110nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479493BDBM479493(ML300-based SC inhibitor 32 | US20240239772, Compo...)
Affinity DataIC50: 111nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479492BDBM479492(ML300-based SC inhibitor 31 | US20240239772, Compo...)
Affinity DataIC50: 119nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685285BDBM685285(US20240239772, Compound 120 | 2-(benzotriazol-1-yl...)
Affinity DataIC50: 120nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685262BDBM685262(US20240239772, Compound 97 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 130nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685256BDBM685256(US20240239772, Compound 91 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 130nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479482BDBM479482(ML300-based SC inhibitor 21 | US20240239772, Compo...)
Affinity DataIC50: 150nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685253BDBM685253(US20240239772, Compound 88 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 160nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685269BDBM685269(US20240239772, Compound 104 | 2-(benzotriazol-1-yl...)
Affinity DataIC50: 170nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479501BDBM479501(ML300-based SC inhibitor 40 | US20240239772, Compo...)
Affinity DataIC50: 171nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479493BDBM479493(ML300-based SC inhibitor 32 | US20240239772, Compo...)
Affinity DataIC50: 176nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685251BDBM685251(US20240239772, Compound 86 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 180nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685270BDBM685270(US20240239772, Compound 105 | 2-(benzotriazol-1-yl...)
Affinity DataIC50: 180nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479499BDBM479499(ML300-based SC inhibitor 38 | US20240239772, Compo...)
Affinity DataIC50: 197nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685275BDBM685275(US20240239772, Compound 110 | 2-(benzotriazol-1-yl...)
Affinity DataIC50: 200nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479498BDBM479498(ML300-based SC inhibitor 37 | US20240239772, Compo...)
Affinity DataIC50: 206nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479499BDBM479499(ML300-based SC inhibitor 38 | US20240239772, Compo...)
Affinity DataIC50: 208nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685273BDBM685273(US20240239772, Compound 108 | 2-(benzotriazol-1-yl...)
Affinity DataIC50: 210nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479501BDBM479501(ML300-based SC inhibitor 40 | US20240239772, Compo...)
Affinity DataIC50: 214nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685245BDBM685245(US20240239772, Compound 80 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 220nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685249BDBM685249(US20240239772, Compound 84 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 230nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685280BDBM685280(US20240239772, Compound 115 | 2-(benzotriazol-1-yl...)
Affinity DataIC50: 240nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479489BDBM479489(ML300-based SC inhibitor 28 | US20240239772, Compo...)
Affinity DataIC50: 250nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685241BDBM685241(US20240239772, Compound 76 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 270nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479497BDBM479497(ML300-based SC inhibitor 36 | US20240239772, Compo...)
Affinity DataIC50: 270nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479494BDBM479494(ML300-based SC inhibitor 33 | US20240239772, Compo...)
Affinity DataIC50: 312nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479498BDBM479498(ML300-based SC inhibitor 37 | US20240239772, Compo...)
Affinity DataIC50: 328nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479500BDBM479500(ML300-based SC inhibitor 39 | US20240239772, Compo...)
Affinity DataIC50: 333nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479497BDBM479497(ML300-based SC inhibitor 36 | US20240239772, Compo...)
Affinity DataIC50: 334nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 479500BDBM479500(ML300-based SC inhibitor 39 | US20240239772, Compo...)
Affinity DataIC50: 336nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685265BDBM685265(US20240239772, Compound 100 | 2-(benzotriazol-1-yl...)
Affinity DataIC50: 340nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685274BDBM685274(US20240239772, Compound 109 | 2-(benzotriazol-1-yl...)
Affinity DataIC50: 340nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685261BDBM685261(US20240239772, Compound 96 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 350nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 685239BDBM685239(US20240239772, Compound 74 | 2-(benzotriazol-1-yl)...)
Affinity DataIC50: 350nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

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