Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 6447
TargetAlpha-1A adrenergic receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  0.880nMAssay Description:Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129716(US8802672, 1)
Affinity DataKi: <1nMAssay Description:Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129721(US8802672, 11)
Affinity DataKi: <1nMAssay Description:Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129720(US8802672, 10)
Affinity DataKi: <1nMAssay Description:Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129717(US8802672, 2)
Affinity DataKi:  2nMAssay Description:Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM6775(US8802672, 8)
Affinity DataKi:  2nMAssay Description:Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129719(US8802672, 7)
Affinity DataKi:  2nMAssay Description:Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129718(US8802672, 6)
Affinity DataKi:  2nMAssay Description:Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129721(US8802672, 11)
Affinity DataKi:  10nMAssay Description:D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129720(US8802672, 10)
Affinity DataKi:  10nMAssay Description:D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129719(US8802672, 7)
Affinity DataKi:  10nMAssay Description:D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  13nMAssay Description:D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  13nMAssay Description:Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetAlpha-1A adrenergic receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  25.1nMAssay Description:Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129718(US8802672, 6)
Affinity DataKi:  35nMAssay Description:D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM6775(US8802672, 8)
Affinity DataKi:  35nMAssay Description:D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129717(US8802672, 2)
Affinity DataKi:  35nMAssay Description:D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129716(US8802672, 1)
Affinity DataKi:  35nMAssay Description:D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(3) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  76nMAssay Description:Binding assays were carried out on rat recombinant D3 receptors (Perkin-Elmer, Cat. No. 6110139) expressed in Sf9 cells using [3H]spiperone (0.44-1.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  96nMAssay Description:D2 receptor binding was determined as described by Creese et al. (Eur. J. Pharmacol., 60:55-66, 1979) on rat brain striatal membrane preparation usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetAlpha-1A adrenergic receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129717(US8802672, 2)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetAlpha-1A adrenergic receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129716(US8802672, 1)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetAlpha-1A adrenergic receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129721(US8802672, 11)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetAlpha-1A adrenergic receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129720(US8802672, 10)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetAlpha-1A adrenergic receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129719(US8802672, 7)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetAlpha-1A adrenergic receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM129718(US8802672, 6)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetAlpha-1A adrenergic receptor(Rat)
Richter Gedeon

US Patent
LigandPNGBDBM6775(US8802672, 8)
Affinity DataKi: >1.00E+3nMAssay Description:Alpha-1 receptor binding studies were performed according to the methods described by Greengrass and Bremner (Eur. J. Pharmacol., 55:323-326, 1979) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent