Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 7112
TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 19.4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 20.9nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 29.5nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM175098(US9115116, 6b)
Affinity DataIC50: 34nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432563(CHEMBL2347011 | US9115116, 8b)
Affinity DataIC50: 34nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM175097(US9115116, 6a)
Affinity DataIC50: 36.5nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432564(CHEMBL2347010 | US9115116, 8a)
Affinity DataIC50: 36.5nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM175098(US9115116, 6b)
Affinity DataIC50: 53.8nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432563(CHEMBL2347011 | US9115116, 8b)
Affinity DataIC50: 53.8nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432562(CHEMBL2347005 | US9115116, 12a)
Affinity DataIC50: 54.1nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 101nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432562(CHEMBL2347005 | US9115116, 12a)
Affinity DataIC50: 122nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM175098(US9115116, 6b)
Affinity DataIC50: 125nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432563(CHEMBL2347011 | US9115116, 8b)
Affinity DataIC50: 125nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM175097(US9115116, 6a)
Affinity DataIC50: 127nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432564(CHEMBL2347010 | US9115116, 8a)
Affinity DataIC50: 127nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432562(CHEMBL2347005 | US9115116, 12a)
Affinity DataIC50: 140nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM175097(US9115116, 6a)
Affinity DataIC50: 159nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432564(CHEMBL2347010 | US9115116, 8a)
Affinity DataIC50: 159nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432564(CHEMBL2347010 | US9115116, 8a)
Affinity DataIC50: 463nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM175097(US9115116, 6a)
Affinity DataIC50: 463nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432562(CHEMBL2347005 | US9115116, 12a)
Affinity DataIC50: 658nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM50432563(CHEMBL2347011 | US9115116, 8b)
Affinity DataIC50: 882nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM175098(US9115116, 6b)
Affinity DataIC50: 882nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 1.19E+4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 1.63E+4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 2.59E+4nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
US Patent