Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 7185
TargetD(2) dopamine receptor(Human)
Neurogastrx

US Patent
LigandPNGBDBM179867(US9132134, Metopimazine (NG101) | US11147820, Comp...)
Affinity DataKi:  0.0700nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
Neurogastrx

US Patent
LigandPNGBDBM179867(US9132134, Metopimazine (NG101) | US11147820, Comp...)
Affinity DataKi:  0.610nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Neurogastrx

US Patent
LigandPNGBDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  1.30nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
Neurogastrx

US Patent
LigandPNGBDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataKi:  7.5nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetHistamine H1 receptor(Human)
Neurogastrx

US Patent
LigandPNGBDBM179867(US9132134, Metopimazine (NG101) | US11147820, Comp...)
Affinity DataKi:  8.40nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Neurogastrx

US Patent
LigandPNGBDBM179868(US9132134, Metopimazine-Acid (NG102) | US11147820,...)
Affinity DataKi:  14nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
Neurogastrx

US Patent
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKi:  16nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Neurogastrx

US Patent
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKi:  64nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
Neurogastrx

US Patent
LigandPNGBDBM179868(US9132134, Metopimazine-Acid (NG102) | US11147820,...)
Affinity DataKi: >100nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetHistamine H1 receptor(Human)
Neurogastrx

US Patent
LigandPNGBDBM179868(US9132134, Metopimazine-Acid (NG102) | US11147820,...)
Affinity DataKi:  140nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent