Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 945
TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300236BDBM300236(tert-butyl 3-[2-(m- tolyl)ethynyl]-3a,4,5,6a- tetr...)
Affinity DataIC50: 3.65nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300227BDBM300227(tert-butyl 3-[2-(3- chlorophenyl)ethynyl]- 3a,4,5,...)
Affinity DataIC50: 3.87nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300230BDBM300230(3-[2-(3-chlorophenyl)ethynyl]- N-ethyl-N-isopropyl...)
Affinity DataIC50: 6.99nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300238BDBM300238([3-[2-(m-tolyl)ethynyl]- 3a,4,5,6a- tetrahydropyrr...)
Affinity DataIC50: 10.6nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300234BDBM300234([3-[2-(3-chlorophenyl)ethynyl]- 3a,4,5,6a- tetrahy...)
Affinity DataIC50: 12.5nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300240BDBM300240(N,N-diethyl-3-[2-(m- tolyl)ethynyl]-3a,4,5,6a- tet...)
Affinity DataIC50: 14.8nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300235BDBM300235([3-[2-(3-chlorophenyl)ethynyl]- 3a,4,5,6a- tetrahy...)
Affinity DataIC50: 15nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300237BDBM300237([3-[2-(m-tolyl)ethynyl]- 3a,4,5,6a- tetrahydropyrr...)
Affinity DataIC50: 17nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300241BDBM300241(N-methoxy-N-methyl-3-[2-(m- tolyl)ethynyl]-3a,4,5,...)
Affinity DataIC50: 22nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300232BDBM300232([3-[2-(3-chlorophenyl)ethynyl]- 3a,4,5,6a- tetrahy...)
Affinity DataIC50: 24.8nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300228BDBM300228([3-[2-(3-chlorophenyl)ethynyl]- 3a,4,5,6a- tetrahy...)
Affinity DataIC50: 29.6nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300239BDBM300239(morpholino-[3-[2-(m- tolyl)ethynyl]-3a,4,5,6a- tet...)
Affinity DataIC50: 50nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300233BDBM300233(3-[2-(3-chlorophenyl)ethynyl]- N,N-dimethyl-3a,4,5...)
Affinity DataIC50: 59.2nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300229BDBM300229(ethyl 3-[2-(3- chlorophenyl)ethynyl]- 3a,4,5,6a- t...)
Affinity DataIC50: 81.5nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300242BDBM300242(ethyl 3-[2-(m-tolyl)ethynyl]- 3a,4,5,6a- tetrahydr...)
Affinity DataIC50: 152nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300245BDBM300245(N-methoxy-N-methyl-3-[2-(6- methyl-2-pyridyl)ethyn...)
Affinity DataIC50: 239nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300231BDBM300231(tert-butyl 3-[2-(6-methyl-2- pyridyl)ethynyl]-3a,4...)
Affinity DataIC50: 708nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300243BDBM300243([3-[2-(6-methyl-2- pyridyl)ethynyl]-3a,4,5,6a- tet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300244BDBM300244([3-[2-(6-methyl-2- pyridyl)ethynyl]-3a,4,5,6a- tet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 300246BDBM300246(ethyl 3-[2-(6-methyl-2- pyridyl)ethynyl]-3a,4,5,6a...)
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent