Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 1291
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314731BDBM314731(US9611270, Example 21)
Affinity DataIC50: 1nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314735BDBM314735(US9611270, Example 32)
Affinity DataIC50: 3nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 21-hydroxylase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50358201BDBM50358201(CHEMBL1921976 | US9611270, orteronel)
Affinity DataIC50: 4nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50358201BDBM50358201(CHEMBL1921976 | US9611270, orteronel)
Affinity DataIC50: 4nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314733BDBM314733(US9611270, Example 30)
Affinity DataIC50: 5nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 21-hydroxylase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314740BDBM314740(US9611270, Example 42)
Affinity DataIC50: 8nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 21-hydroxylase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314736BDBM314736(US9611270, Example 33)
Affinity DataIC50: 10nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314740BDBM314740(US9611270, Example 42)
Affinity DataIC50: 120nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 25458BDBM25458(ABT | CHEMBL254328 | CB 7598 | (1S,2R,5S,10R,11S,1...)
Affinity DataIC50: 130nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314736BDBM314736(US9611270, Example 33)
Affinity DataIC50: 150nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314738BDBM314738(US9611270, Example 38)
Affinity DataIC50: 174nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314739BDBM314739(US9611270, Example 39 | US9611270, Example 41)
Affinity DataIC50: 183nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314734BDBM314734(US9611270, Example 31)
Affinity DataIC50: 199nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314732BDBM314732(US9611270, Example 29)
Affinity DataIC50: 208nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314737BDBM314737(US9611270, Example 37)
Affinity DataIC50: 244nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 21-hydroxylase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50435990BDBM50435990(VN/124 | VN/124-1 | TOK-001 | GALETERONE | US96112...)
Affinity DataIC50: 248nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 50435990BDBM50435990(VN/124 | VN/124-1 | TOK-001 | GALETERONE | US96112...)
Affinity DataIC50: 282nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSteroid 21-hydroxylase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 25458BDBM25458(ABT | CHEMBL254328 | CB 7598 | (1S,2R,5S,10R,11S,1...)
Affinity DataIC50: 296nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314730BDBM314730(US9611270, Example 8)
Affinity DataIC50: 428nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 21-hydroxylase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314738BDBM314738(US9611270, Example 38)
Affinity DataIC50: 537nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

TargetSteroid 21-hydroxylase(Human)
University of Kansas

US Patent
LigandChemical structure of BindingDB Monomer ID 314739BDBM314739(US9611270, Example 39 | US9611270, Example 41)
Affinity DataIC50: 831nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent