Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 2765
TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380428BDBM380428(US9926299, 33 | 5-amino-1-(2-(N-methylvinylsulfona...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380427BDBM380427(US9926299, 32 | 5-amino-1-(2-(N-methylpropiolamido...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 303533BDBM303533(US10138229, Example 44 | US9926299, 31 | US1087585...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380425BDBM380425(US9926299, 30 | 5-amino-1-(2-(N-methylacrylamido)e...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380432BDBM380432(US9926299, 41 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380431BDBM380431(US9926299, 37 | 1-(1-acryloylpiperidin-3-yl)-5-ami...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380430BDBM380430(US9926299, 35 | (E)-5-amino-1-(2-(4-(dimethylamino...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380429BDBM380429(US9926299, 34 | 5-amino-1-(2-(2-chloro-N-methylace...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380420BDBM380420(US9926299, 26 | 5-amino-3-(4-phenoxyphenyl)-1-(1-p...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380419BDBM380419(US9926299, 25 (S-isomer))
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380418BDBM380418(US9926299, 25 (R-isomer))
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380082BDBM380082(US9926299, 25 | 1-(1-acryloylpyrrolidin-3-yl)-5-am...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380424BDBM380424(US9926299, 29 | (E)-5-amino-1-(1-(4-(dimethylamino...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380423BDBM380423(US9926299, 28 | 5-amino-1-(1-(2-chloroacetyl)piper...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 295011BDBM295011(US10112922, Compound 1 | US9926299, 27 (R-isomer))
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380421BDBM380421(US9926299, 27 | 5-amino-3-(4-phenoxyphenyl)-1-(1-(...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380436BDBM380436(US9926299, 45 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380435BDBM380435(US9926299, 44 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380434BDBM380434(US9926299, 43 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380433BDBM380433(US9926299, 42 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380440BDBM380440(US9926299, 49 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380439BDBM380439(US9926299, 48 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380438BDBM380438(US9926299, 47 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380437BDBM380437(US9926299, 46 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 303543BDBM303543(US10138229, Example 54 | US10266513, Example 127 |...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380038BDBM380038(US9926299, 15 | 1-(1-acryloylpiperidin-3-yl)-5-(2-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380024BDBM380024(US9926299, 13 | 1-(1-acryloylpiperidin-3-yl)-5-(2-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380018BDBM380018(US9926299, 6 | 1-(1-acryloylpiperidin-3-yl)-5-(eth...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380071BDBM380071(US9926299, 24 | 1-(1-acryloylpiperidin-4-yl)-5-ami...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 377832BDBM377832(1-[(3S)-1-acryloyl piperidin-3-yl]-5-amino-3-(4-ph...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380057BDBM380057(US9926299, 22 | 1-(1-acryloylpiperidin-3-yl)-5-ami...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380053BDBM380053(US9926299, 20 | 5-amino-1-cyclohexyl-3-(4-phenoxyp...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380015BDBM380015(US9926299, 2 | (R)-1-(1-acryloylpiperidin-3-yl)-5-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 380007BDBM380007(US9926299, 1 | 1-(1-acryloylpiperidin-3-yl)-5-(met...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent