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Target
Zinc finger protein mex-5
Ligand
BDBM52934
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52934
Synonyms:
MLS000860958 | N'4-benzoyl-2-(3-pyridyl)-1,3-thiazole-4-carbohydrazide | N'-(phenylcarbonyl)-2-pyridin-3-yl-1,3-thiazole-4-carbohydrazide | N'-benzoyl-2-(3-pyridinyl)-4-thiazolecarbohydrazide | N'-benzoyl-2-(3-pyridyl)thiazole-4-carbohydrazide | N'-benzoyl-2-pyridin-3-yl-1,3-thiazole-4-carbohydrazide | SMR000459742 | cid_2824173
Type:
Small organic molecule
Emp. Form.:
C16H12N4O2S
Mol. Mass.:
324.357
SMILES:
O=C(NNC(=O)c1ccccc1)c1csc(n1)-c1cccnc1
Structure:
Search PDB for entries with ligand similarity: