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Target
Leukotriene B4 receptor 1
Ligand
BDBM50000546
Substrate
n/a
Meas. Tech.
ChEBML_98491
IC50
>2000±n/a nM
Citation
 Lau, CK; Bélanger, PC; Dufresne, C; Scheigetz, J; Therien, M; Fitzsimmons, B; Young, RN; Ford-Hutchinson, AW; Riendeau, D; Denis, D Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase. J Med Chem 35:1299-318 (1992) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50000546
Synonyms:
3,4,5,6-Tetrahydroxy-tetrahydro-pyran-2-carboxylic acid 2-(2-ethyl-phenyl)-6-(3-phenoxy-propyl)-2,3-dihydro-benzofuran-5-yl ester | CHEMBL423111
Type:
Small organic molecule
Emp. Form.:
C31H34O9
Mol. Mass.:
550.5963
SMILES:
CCc1ccccc1C1Cc2cc(OC(=O)C3O[C@@H](O)[C@H](O)[C@@H](O)[C@H]3O)c(CCCOc3ccccc3)cc2O1
Structure:
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