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Target
D(2) dopamine receptor
Ligand
BDBM50496563
Substrate
n/a
Meas. Tech.
ChEMBL_1299395 (CHEMBL3136930)
Ki
7.5±n/a nM
Citation
 Tu, Z; Li, S; Li, A; Taylor, M; Ho, D; Malik, M; Luedtke, RR; Mach, RH Synthesis and  Medchemcomm 4:1283-1289 (2013) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50496563
Synonyms:
CHEMBL3133873
Type:
Small organic molecule
Emp. Form.:
C28H33FN4O7
Mol. Mass.:
556.5826
SMILES:
OC(=O)C(O)=O.COc1ccc2[nH]cc(C(=O)NC\C=C\CN3CCN(CC3)c3ccccc3OCCF)c2c1
Structure:
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