Reaction Details Report a problem with these data
Target
Anionic trypsin
Ligand
BDBM50067526
Substrate
n/a
Meas. Tech.
ChEMBL_212181 (CHEMBL817745)
Ki
18000±n/a nM
Citation
 Gabriel, B; Stubbs, MT; Bergner, A; Hauptmann, J; Bode, W; Stürzebecher, J; Moroder, L Design of benzamidine-type inhibitors of factor Xa. J Med Chem 41:4240-50 (1998) [PubMed]  Article 
Target
Name:
Anionic trypsin
Synonyms:
Anionic trypsin | TRY2_BOVIN | Trypsin II
Type:
PROTEIN
Mol. Mass.:
26281.39
Organism:
Bos taurus
Description:
ChEMBL_212177
Residue:
247
Sequence:
MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS
  
Inhibitor
Name:
BDBM50067526
Synonyms:
2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetylamino]-3-(4-carbamimidoyl-phenyl)-propionic acid | CHEMBL341933
Type:
Small organic molecule
Emp. Form.:
C19H22N6O5S
Mol. Mass.:
446.48
SMILES:
NC(=N)c1ccc(CC(NC(=O)CNS(=O)(=O)c2ccc(cc2)C(N)=N)C(O)=O)cc1
Structure:
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