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Target
Polyphenol oxidase 2
Ligand
BDBM197302
Substrate
n/a
Meas. Tech.
ChEMBL_1925065 (CHEMBL4428021)
IC50
710000±n/a nM
Citation
 Oyama, T; Takahashi, S; Yoshimori, A; Yamamoto, T; Sato, A; Kamiya, T; Abe, H; Abe, T; Tanuma, SI Discovery of a new type of scaffold for the creation of novel tyrosinase inhibitors. Bioorg Med Chem 24:4509-4515 (2016) [PubMed]  Article 
Target
Name:
Polyphenol oxidase 2
Synonyms:
Monophenol monooxygenase | Monophenol oxidase | PPO2 | PPO2_AGABI | Tyrosinase
Type:
Protein
Mol. Mass.:
63923.66
Organism:
Agaricus bisporus (Common mushroom)
Description:
O42713
Residue:
556
Sequence:
MSLIATVGPTGGVKNRLNIVDFVKNEKFFTLYVRSLELLQAKEQHDYSSFFQLAGIHGLPFTEWAKERPSMNLYKAGYCTHGQVLFPTWHRTYLSVLEQILQGAAIEVAKKFTSNQTDWVQAAQDLRQPYWDWGFELMPPDEVIKNEEVNITNYDGKKISVKNPILRYHFHPIDPSFKPYGDFATWRTTVRNPDRNRREDIPGLIKKMRLEEGQIREKTYNMLKFNDAWERFSNHGISDDQHANSLESVHDDIHVMVGYGKIEGHMDHPFFAAFDPIFWLHHTNVDRLLSLWKAINPDVWVTSGRNRDGTMGIAPNAQINSETPLEPFYQSGDKVWTSASLADTARLGYSYPDFDKLVGGTKELIRDAIDDLIDERYGSKPSSGARNTAFDLLADFKGITKEHKEDLKMYDWTIHVAFKKFELKESFSLLFYFASDGGDYDQENCFVGSINAFRGTAPETCANCQDNENLIQEGFIHLNHYLARDLESFEPQDVHKFLKEKGLSYKLYSRGDKPLTSLSVKIEGRPLHLPPGEHRPKYDHTQARVVFDDVAVHVIN
  
Inhibitor
Name:
BDBM197302
Synonyms:
Benzoic acid | SAMPL4, O1
Type:
Small organic molecule
Emp. Form.:
C7H6O2
Mol. Mass.:
122.1213
SMILES:
OC(=O)c1ccccc1
Structure:
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