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Target
Ras-related protein Rab-6A
Ligand
BDBM50540838
Substrate
n/a
Meas. Tech.
ChEMBL_1983101 (CHEMBL4616363)
Kd
20000±n/a nM
Citation
 Brancaccio, D; Di Maro, S; Cerofolini, L; Giuntini, S; Fragai, M; Luchinat, C; Tomassi, S; Limatola, A; Russomanno, P; Merlino, F; Novellino, E; Carotenuto, A HOPPI-NMR: Hot-Peptide-Based Screening Assay for Inhibitors of Protein-Protein Interactions by NMR. ACS Med Chem Lett 11:1047-1053 (2020) [PubMed]  Article 
Target
Name:
Ras-related protein Rab-6A
Synonyms:
RAB6 | RAB6A | RAB6A_HUMAN | Rab-6 | Ras-related protein Rab-6A
Type:
PROTEIN
Mol. Mass.:
23590.50
Organism:
Homo sapiens
Description:
ChEMBL_117308
Residue:
208
Sequence:
MSTGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSEGGCSC
  
Inhibitor
Name:
BDBM50540838
Synonyms:
CHEMBL4635206
Type:
Small organic molecule
Emp. Form.:
C95H138N22O30
Mol. Mass.:
2068.2416
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O |r|
Structure:
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