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Target
Carboxypeptidase M
Ligand
BDBM50135939
Substrate
n/a
Meas. Tech.
ChEMBL_45790 (CHEMBL660086)
IC50
13±n/a nM
Citation
 Barrow, JC; Nantermet, PG; Stauffer, SR; Ngo, PL; Steinbeiser, MA; Mao, SS; Carroll, SS; Bailey, C; Colussi, D; Bosserman, M; Burlein, C; Cook, JJ; Sitko, G; Tiller, PR; Miller-Stein, CM; Rose, M; McMasters, DR; Vacca, JP; Selnick, HG Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics. J Med Chem 46:5294-7 (2003) [PubMed]  Article 
Target
Name:
Carboxypeptidase M
Synonyms:
CBPM_HUMAN | CPM
Type:
PROTEIN
Mol. Mass.:
50519.81
Organism:
Homo sapiens (Human)
Description:
ChEMBL_45790
Residue:
443
Sequence:
MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSLLHIFFK
  
Inhibitor
Name:
BDBM50135939
Synonyms:
3-(4,4-Diamino-but-3-enylsulfanyl)-2-mercaptomethyl-propionic acid | CHEMBL150332
Type:
Small organic molecule
Emp. Form.:
C8H16N2O2S2
Mol. Mass.:
236.355
SMILES:
NC(=N)CCCSCC(CS)C(O)=O
Structure:
Search PDB for entries with ligand similarity: