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Target
Transporter
Ligand
BDBM50218674
Substrate
n/a
Meas. Tech.
ChEMBL_457102 (CHEMBL924478)
Ki
17900±n/a nM
Citation
 Vercouillie, J; Deuther-Conrad, W; Scheunemann, M; Emond, P; Fischer, S; Funke, U; Steinbach, J; Guilloteau, D; Brust, P New fluoro-diphenylchalcogen derivatives to explore the serotonin transporter by PET. Bioorg Med Chem Lett 17:4991-5 (2007) [PubMed]  Article 
Target
Name:
Transporter
Synonyms:
Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters
Type:
PROTEIN
Mol. Mass.:
66787.87
Organism:
Rattus norvegicus
Description:
ChEMBL_1463061
Residue:
597
Sequence:
MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAYGITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
  
Inhibitor
Name:
BDBM50218674
Synonyms:
3-amino-4-(2-((dimethylamino)methyl)-4-fluorophenylthio)benzonitrile | CHEMBL246120
Type:
Small organic molecule
Emp. Form.:
C16H16FN3S
Mol. Mass.:
301.382
SMILES:
CN(C)Cc1cc(F)ccc1Sc1ccc(cc1N)C#N
Structure:
Search PDB for entries with ligand similarity: