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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50286547
Substrate
n/a
Meas. Tech.
ChEBML_195356
IC50
2288±n/a nM
Citation
 Young, SD; Amblard, MC; Britcher, SF; Grey, VE; Tran, LO; Lumma, WC; Huff, JR; Schleif, WA; Emini, EE; O'Brien, JA; Pettibone, DJ 2-Heterocyclic indole-3-sulfones as inhibitors of HIV-1 reverse transcriptase Bioorg Med Chem Lett 5:491-496 (1995)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50286547
Synonyms:
3-Benzenesulfonyl-5-chloro-2-(1,4,5,6-tetrahydro-pyrimidin-2-yl)-1H-indole | CHEMBL343642
Type:
Small organic molecule
Emp. Form.:
C18H16ClN3O2S
Mol. Mass.:
373.857
SMILES:
Clc1ccc2[nH]c(c(c2c1)S(=O)(=O)c1ccccc1)C1=NCCCN1 |t:22|
Structure:
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